American Journal of Kidney Diseases
Volume 49, Issue 2 , Pages 330-335 , February 2007

Autonomic Nervous System Function in Chronic Hypotension Associated With Bartter and Gitelman Syndromes

Received 5 June 2006 ,Accepted 26 October 2006.

References 

  1. Naesens M, Steels P, Verberckmoes R, Vanrenterghem Y, Kuypers D. Bartter’s and Gitelman’s syndromes: From gene to clinic. Nephron Physiol. 2004;96:65–78
  2. Calò LA, Pessina AC, Semplicini A. Angiotensin II signaling in the Bartter’s and Gitelman’s syndromes, a negative human model of hypertension. High Blood Press Cardiovasc Prev. 2005;12:17–26
  3. Calo LA. Vascular tone control in humans: Insights from studies in Bartter’s/Gitelman’s syndromes. Kidney Int. 2006;69:963–966
  4. Calò L, Davis PA, Semplicini A. Bartter’s/Gitelman’s syndrome: A model for the relationships between hypertension, angiotensin II, oxidative stress and remodeling. Clin Nephrol. 2003;59:393–394
  5. Cruz DN, Shaer AJ, Bia MJ, et al. Gitelman’s syndrome revisited: An evaluation of symptoms and health-related quality of life. Kidney Int. 2001;59:710–717
  6. Lasaridis AN, Pitsariotis B, Syrganis C, Gatzis C, Brettou E, Tourkantonis A. Severe orthostatic hypotension due to Bartter’s syndrome. Clin Nephrol. 1987;28:105–156
  7. Smit AA, Halliwill JR, Low PA, Wieling W. Pathophysiological basis of orthostatic hypotension in autonomic failure. J Physiol. 1999;519:1–10
  8. Goldstein DS, Robertson D, Esler M, Straus SE, Eisenhofer G. Dysautonomias: Clinical disorders of the autonomic nervous system. Ann Intern Med. 2002;137:753–763
  9. Mathias CJ, Kimber JR. Postural hypotension: Causes, clinical features, investigation, and management. Annu Rev Med. 1999;50:317–336
  10. O’Brien E, Murphy J, Tyndall A, et al. Twenty-four-hour ambulatory blood pressure in men and women aged 17 to 80 years: The Allied Irish Bank Study. J Hypertens. 1991;9:355–360
  11. Sartori M, Pessina AC. Orthostatic hypotension and supine hypertension in pure autonomic failure. Ital Heart J Suppl. 2004;5:S879–S883
  12. Tank J, Diedrich A, Szczech E, Luft FC, Jordan J. Baroreflex regulation of heart rate and sympathetic vasomotor tone in women and men. Hypertension. 2005;45:1159–1164
  13. Raamat R, Talts J, Jagomagi K, Kivastik J, Lansimies E, Jurvelin J. Simultaneous application of differential servo-oscillometry and volume-clamp plethysmography for continuous non-invasive recording of the finger blood pressure response to a hand postural change. J Med Eng Technol. 2006;30:139–144
  14. Vogel ER, Sandroni P, Low PA. Blood pressure recovery from Valsalva maneuver in patients with autonomic failure. Neurology. 2005;65:1533–1537
  15. Mathias CJ, Bannister R. Investigation of autonomic disorders. In:  Mathias CJ,  Bannister R editor. Autonomic Failure. Oxford, UK: Oxford University; 1999;p. 169–193
  16. Boer P, Henè RJ, Koomans HA, Nieuwenhuis MG, Geyskes GG, Mees EJ. Blood and extracellular fluid volume in patients with Bartter’s syndrome. Arch Intern Med. 1983;143:1902–1905
  17. Calò L, Ceolotto G, Milani M, et al. Abnormalities of Gq-mediated cell signaling in Bartter and Gitelman syndromes. Kidney Int. 2001;60:882–889
  18. Calò L, Davis PA, Semplicini A. Reduced content of alpha subunit of Gq protein in monocytes of Bartter and Gitelman syndromes: Relationship with vascular hyporeactivity. Kidney Int. 2002;61:353–354
  19. Pagnin E, Davis PA, Sartori M, Semplicini A, Pessina AC, Calò LA. Rho kinase and PAI-1 in Bartter’s/Gitelman’s syndromes: Relationship to angiotensin II signaling. J Hypertens. 2004;22:1963–1969
  20. Pagnin E, Semplicini A, Sartori M, Pessina AC, Calò LA. Reduced mRNA and protein content of Rho guanine nucleotide exchange factor (RhoGEF) in Bartter’s and Gitelman’s syndromes (Relevance for the pathophysiology of hypertension). Am J Hypertens. 2005;18:1200–1205
  21. Calò LA, Pagnin E, Davis PA, et al. Increased expression of regulator of G protein signaling–2 (RGS-2) in Bartter’s/Gitelman’s sydrome (A role in the control of vascular tone and implication for hypertension). J Clin Endocrinol Metab. 2004;89:4153–4157
  22. Calò L, Davis PA, Milani M, et al. Increased endothelial nitric oxide synthase mRNA level in Bartter’s and Gitelman’s syndrome (Relationship to vascular reactivity). Clin Nephrol. 1999;51:12–17
  23. Calò L, D’Angelo A, Cantaro S, et al. Increased urinary NO2–/NO3– and cyclic GMP levels in patients with Bartter’s syndrome: Relationship to vascular reactivity. Am J Kidney Dis. 1996;27:874–887

 Support: None. Potential conflicts of interest: None.Originally published online as doi:10.1053/j.ajkd.2006.10.023 on December 26, 2006.

PII: S0272-6386(06)01687-8

doi: 10.1053/j.ajkd.2006.10.023

American Journal of Kidney Diseases
Volume 49, Issue 2 , Pages 330-335 , February 2007

Article Tools