American Journal of Kidney Diseases
Volume 49, Issue 6 , Pages 725-728 , June 2007

Treatment of Polycystic Liver Disease: One Size Does Not Fit All

  • Vicente E. Torres, MD, PhD

      Affiliations

    • Corresponding Author InformationAddress correspondence to Vicente E. Torres, MD, PhD, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905.

References 

  1. Bae KT, Zhu F, Guay-Woodford LM, et al. CRISP: Magnetic resonance imaging evaluation of hepatic cysts in early autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol. 2006;1:64–69
  2. Li A, Davila S, Furu L, et al. Mutations in PRKCSH cause isolated sutosomal dominant polycystic liver disease. Am J Hum Genet. 2003;72:691–703
  3. Drenth JP, Te Morsche RH, Smink R, Bonifacino JS, Jansen JB. Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease. Nat Genet. 2003;33:345–347
  4. Davila S, Furu L, Gharavi AG, et al. Mutations in SEC63 cause autosomal dominant polycystic liver disease. Nat Genet. 2004;36:575–577
  5. Alvaro D, Mancino MG, Onori P, et al. Estrogens and the pathophysiology of the biliary tree. World J Gastroenterol. 2006;12:3537–3545
  6. Sherstha R, McKinley C, Russ P, et al. Postmenopausal estrogen therapy selectively stimulates hepatic enlargement in women with autosomal dominant polycystic kidney disease. Hepatology. 1997;26:1282–1286
  7. Arnold HL, Harrison SA. New advances in evaluation and management of patients with polycystic liver disease. Am J Gastroenterol. 2005;100:2569–2582
  8. Takei R, Ubara Y, Hoshino J, et al. Percutaneous transcatheter hepatic artery embolization for liver cysts in autosomal dominant polycystic kidney disease. Am J Kidney Dis. 2007;49:744–752
  9. Grams J, Teh SH, Torres VE, Andrews J, Nagorney DM. Inferior vena cava stenting: A safe and effective treatment for intractable ascites in patients with polycystic liver disease. J Gastrointest Surg. 2007;(Article In Press)
  10. Mudge DW, Taylor J, Bannister KM. Hepatic vein stenting for recurrent ascites in polycystic liver and kidney disease. Nephrol Dial Transplant. 2005;20:2566–2568
  11. Blonski WC, Campbell MS, Faust T, Metz DC. Successful aspiration and ethanol sclerosis of a large, symptomatic, simple liver cyst: case presentation and review of the literature. World J Gastroenterol. 2006;12:2949–2954
  12. Yoshida H, Onda M, Tajiri T, et al. Long-term results of multiple minocycline hydrochloride injections for the treatment of symptomatic solitary hepatic cyst. J Gastroenterol Hepatol. 2003;18:595–598
  13. Gigot JF, Metairie S, Etienne J. The surgical management of congenital liver cysts. Surg Endosc. 2001;15:357–363
  14. Fiamingo P, Tedeschi U, Veroux M. Laparoscopic treatment of simple hepatic cysts and polycystic liver disease. Surg Endosc. 2003;17:623–626
  15. Que F, Nagorney D, Gross J, Torres V. Liver resection and cyst fenestration in the treatment of severe polycystic liver disease. Gastroenterology. 1995;108:487–494
  16. Ueno T, Barri YM, Netto GJ. Liver and kidney transplantation for polycystic liver and kidney-renal function and outcome. Transplantation. 2006;82:501–507
  17. Kirchner GI, Rifai K, Cantz T. Outcome and quality of life in patients with polycystic liver disease after liver or combined liver-kidney transplantation. Liver Transpl. 2006;12:1268–1277
  18. Arrazola L, Moonka D, Gish RG, Everson GT. Model for end-stage liver disease (MELD) exception for polycystic liver disease. Liver Transpl. 2006;12(Suppl 3):S110–S111
  19. Torres VE, Harris PC. Mechanisms of disease: autosomal dominant and recessive polycystic kidney diseases. Nat Clin Pract Nephrol. 2006;2:40–54
  20. Masyuk TV, Masyuk AI, Torres VE, Harris PC, LaRusso NF. Octreotide inhibits hepatic cystogenesis in vitro and in vivo: a new therapeutic approach for treatment of polycystic liver diseases. Gastroenterology. 2007;132:1104–1116
  21. Hogan, MC: Octreotide in Severe Polycystic Liver Disease. Available at: http://clinicaltrials.gov/ct/show/NCT00426153. Accessed April 16, 2007.

 Support: None. Potential conflicts of interest: None.

PII: S0272-6386(07)00728-7

doi: 10.1053/j.ajkd.2007.04.009

American Journal of Kidney Diseases
Volume 49, Issue 6 , Pages 725-728 , June 2007

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