American Journal of Kidney Diseases
Volume 50, Issue 5 , Pages 830-833 , November 2007

Nodular Glomerulosclerosis in a Kidney Transplant Recipient Who Smokes

  • Manish Suneja, MD

      Affiliations

    • Department of Internal Medicine, Nephrology Division, University of Iowa Hospitals and Clinics, Iowa City, IA
    • ,
  • Amina Khan, MD

      Affiliations

    • Department of Internal Medicine, Nephrology Division, University of Iowa Hospitals and Clinics, Iowa City, IA
    • ,
  • Daniel A. Katz, MD

      Affiliations

    • Department of Surgery, University of Iowa Hospitals and Clinics, Veterans Administration Medical Center, Iowa City, IA
    • ,
  • Roberto Kalil, MD

      Affiliations

    • Department of Internal Medicine, Nephrology Division, University of Iowa Hospitals and Clinics, Iowa City, IA
    • ,
  • Ramesh Nair, MD

      Affiliations

    • Department of Pathology, University of Iowa Hospitals and Clinics, Veterans Administration Medical Center, Iowa City, IA.
    • Corresponding Author InformationAddress correspondence to Ramesh Nair, MD, Department of Pathology, 200 Hawkins Dr, RCP 5243, Iowa City, IA 52242-1009.

Received 20 February 2007 ,Accepted 13 April 2007.

References 

  1. Orth S, Ritz E. The renal risks of smoking: An update. Curr Opin Nephrol Hypertens. 2002;11:483–488
  2. Jaimes E, DeMaster E, Tian R, Raij L. Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation. Arterioscler Thromb Vasc Biol. 2004;24:1031–1036
  3. Jaimes E, Tian R, Raij L. Nicotine: The link between cigarette smoking and the progression of renal injury?. Am J Physiol Heart Circ Physiol. 2007;292:H76–H82
  4. Sung R, Althoen M, Howell T, Ojo A, Merion R. Excess risk of renal allograft loss associated with cigarette smoking. Transplantation. 2001;71:1752–1757
  5. Doyle S, Matas A, Gillingham K, Rosenberg M. Predicting clinical outcome in the elderly renal transplant recipient. Kidney Int. 2000;57:2144–2150
  6. Markowitz G, Lin J, Valerie A, Avila C, Nasr S, D’Agati V. Idiopathic nodular glomerulosclerosis is a distinct clinicopathologic entity linked to hypertension and smoking. Hum Pathol. 2002;33:826–835
  7. Liang K, Greene E, Oei L, Lewin M, Lager D, Sethi S. Nodular glomerulosclerosis: Renal lesions in chronic smokers mimic chronic thrombotic microangiopathy and hypertensive lesions. Am J Kidney Dis. 2007;49:552–559

 Originally published online as doi:10.1053/j.ajkd.2007.04.029 on August 1, 2007.

PII: S0272-6386(07)00944-4

doi: 10.1053/j.ajkd.2007.04.029

American Journal of Kidney Diseases
Volume 50, Issue 5 , Pages 830-833 , November 2007

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