American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages 326-330 , February 2008

Malakoplakia of the Kidney

  • Akimitsu Kobayashi, MD

      Affiliations

    • Department of Internal Medicine, Division of Kidney and Hypertension, The Jikei University School of Medicine, Tokyo, Japan
    • Department of Internal Medicine, Kanagawa Prefectural Hospital, Yokohama, Japan
    • Corresponding Author InformationAddress correspondence to Akimitsu Kobayashi, MD, Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-shimbashi, Minato-ku, Tokyo 105-8471, Japan.
    • ,
  • Yasunori Utsunomiya, MD, PhD

      Affiliations

    • Department of Internal Medicine, Division of Kidney and Hypertension, The Jikei University School of Medicine, Tokyo, Japan
    • ,
  • Midori Kono, PhD

      Affiliations

    • Department of Laboratory Medicine, The Jikei University School of Medicine, Tokyo, Japan
    • ,
  • Yoriko Ito, MD

      Affiliations

    • Department of Internal Medicine, Division of Kidney and Hypertension, The Jikei University School of Medicine, Tokyo, Japan
    • ,
  • Izumi Yamamoto, MD

      Affiliations

    • Department of Internal Medicine, Division of Kidney and Hypertension, The Jikei University School of Medicine, Tokyo, Japan
    • ,
  • Naoyuki Osaka, MD, PhD

      Affiliations

    • Department of Internal Medicine, Kanagawa Prefectural Hospital, Yokohama, Japan
    • ,
  • Toshio Hasegawa, MD, PhD

      Affiliations

    • Department of Internal Medicine, Kanagawa Prefectural Hospital, Yokohama, Japan
    • ,
  • Sadayori Hoshina, PhD

      Affiliations

    • Department of Laboratory Medicine, The Jikei University School of Medicine, Tokyo, Japan
    • ,
  • Yutaka Yamaguchi, MD, PhD

      Affiliations

    • Department of Pathology, Kashiwa Hospital, The Jikei University School of Medicine, Chiba, Japan.
    • ,
  • Yoshindo Kawaguchi, MD, PhD

      Affiliations

    • Department of Internal Medicine, Kanagawa Prefectural Hospital, Yokohama, Japan
    • ,
  • Tatsuo Hosoya, MD, PhD

      Affiliations

    • Department of Internal Medicine, Division of Kidney and Hypertension, The Jikei University School of Medicine, Tokyo, Japan

Received 15 May 2007 ,Accepted 23 August 2007.

References 

  1. von Hansemann D. Uber malakoplakia der harnblase. Virchows Arch A Pathol Anat Histopathol. 1903;173:302–308
  2. Imai E, Horio M, Nitta K, et al. Estimation of glomerular filtration rate by the MDRD equation modified for Japanese patients with chronic kidney disease. Clin Exp Nephrol. 2007;11:41–50
  3. Stanton MJ, Maxted W. Malakoplakia: A study of the literature and current concepts of pathogenesis, diagnosis and treatment. J Urol. 1981;125:139–146
  4. Michaelis L, Gutmann M. Ueber einschlusse in blasentumoren. Z Klin Med. 1902;47:208–215
  5. Jenkins DAS, Harrison DJ, MacDonald MK, Winney RJ. Mefenamic acid nephropathy: An interstitial and mesangial lesion. Nephrol Dial Transplant. 1988;2:217–220
  6. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215
  7. Altschul SF, Madden TL, Schaffer AA, et al. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 1997;25:3389–3402
  8. Abdou NI, NaPombejara C, Sagawa A, et al. Malakoplakia: Evidence for monocyte lysosomal abnormality correctable by cholinergic agonist in vitro and in vivo. N Engl J Med. 1977;7:1413–1419
  9. McDonald S, Sewell WT. Malakoplakia of the bladder and kidneys. J Bacteriol Pathol. 1913;28:306–321
  10. Dobyan DC, Truong LD, Eknoyan G. Renal malacoplakia reappraised. Am J Kidney Dis. 1993;22:243–252
  11. Albitar S, Genin R, Fen-Chong M, Schohn D, Riviere JP, Serveaux MO. The febrile patient presenting with acute renal failure and enlarged kidneys—Another mode of presentation of malakoplakia. Nephrol Dial Transplant. 1997;12:1724–1726
  12. Tam VKK, Kung WH, Li R, Chan KW. Renal parenchymal malacoplakia: A rare cause of ARF with a review of recent literature. Am J Kidney Dis. 2003;41:E13–E17
  13. Hurwitz G, Reimund E, Mopathy KR, Hellstrom WJ. Bilateral renal parenchymal malacoplakia: A case report. J Urol. 1992;147:115–117
  14. Shabtai M, Anaise D, Frei L, et al. Malakoplakia in renal transplantation: An expression of altered tissue reactivity under immunosuppression. Transplant Proc. 1989;21:3725–3727
  15. van Crevel R, Curfs J, van der Ven AJ, Assmann K, Meis JF, van der Meer JW. Functional and morphological monocyte abnormalities in a patient with malakoplakia. Am J Med. 1998;105:74–77
  16. Esparza AR, McKay DB, Cronan JJ, Chazan JA. Renal parenchymal malakoplakia: Histologic spectrum and its relationship to megalocytic interstitial nephritis and xanthogranulomatous pyelonephritis. Am J Surg Pathol. 1989;13:225–236
  17. Csapo Z, Kuthy E, Lantos J, Ormos J. Experimentally-induced malakoplakia. Am J Pathol. 1975;79:453–464
  18. Mokrzycki MH, Yamase H, Kohn OF. Renal malacoplakia with papillary necrosis and renal failure. Am J Kidney Dis. 1992;19:587–591
  19. van Furth R, van’t Wout JW, Wertheimer PA, Zwrtendijk J. Ciprofloxacin for treatment of malakoplakia. Lancet. 1992;339:148–149
  20. van der Voort HJ, ten Velden JA, Wassenaar RP, Siberbusch J. Malacoplakia: Two case reports and a comparison of treatment modalities. Arch Intern Med. 1996;156:577–583
  21. Stanton MJ, Lynch JH, Maxted WC, Chun BK. Malacoplakia of the bladder: A case report of resolution with bethanechol, trimethoprim-sulfamethoxazole and ascorbic acid. J Urol. 1983;130:1174–1175
  22. Joss N, Morris S, Young B, Geddes C. Granulomatous interstitial nephritis. Clin Am Soc Nephrol. 2007;2:222–230

PII: S0272-6386(07)01494-1

doi: 10.1053/j.ajkd.2007.08.029

American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages 326-330 , February 2008

Article Tools

* Image Usage & Resolution