American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages A33-A34 , February 2008

Quiz Page February 2008: A Hemodialysis Patient With Thickened Skin

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    (A) Lower extremity plaques with weeping blisters and peau d’orange change. (B) Hands demonstrating contractures. (C) Deep biopsy of the skin showing numerous fibroblast-like cells in the dermis, exte

    (A) Lower extremity plaques with weeping blisters and peau d’orange change. (B) Hands demonstrating contractures. (C) Deep biopsy of the skin showing numerous fibroblast-like cells in the dermis, extending into the fascia along subcutaneous septa. (D) Large, epithelioid, or stellate spindle cells extending into and widening the subcutaneous fat lobule septa. The spindle cells are diffusely arranged among thickened collagen bundles.

 Case provided and authored by Fuad Jan, MD,1 Hina Mahboob, MD,2 and Allan B. Schwartz, MD,1 1Drexel University College of Medicine, Philadelphia, PA, and 2Abington Memorial Hospital, Abington, PA.

 Support: None.

 Financial disclosure: None.

PII: S0272-6386(07)01584-3

doi: 10.1053/j.ajkd.2007.12.001

American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages A33-A34 , February 2008