American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages 345-346, February 2008

In Reply

Wake Forest University School of Medicine, Winston-Salem, North Carolina

Article Outline

 

In Reply:

We thank Dr Jenkins for his comment regarding the role of iron deficiency in CKD itch. We agree that, historically, iron deficiency anemia has been mentioned in anecdotal reports to be involved in the etiopathogenesis of generalized pruritus as well as in dialysis patients. However, DOPPS, the large Dialysis Outcomes and Practice Patterns Study of more than 18,000 hemodialysis patients, did not find any correlation between low ferritin levels, which have a direct correlation with the total amount of iron stored in the body, and pruritus.1 Pruritus continues to be a common problem among hemodialysis patients; despite erythropoietin use, 42% of patients still itch. Therefore it seems iron deficiency anemia is not a common cause for CKD itch.

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Acknowledgements 

Support: None.

Financial Disclosure: None.

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Reference 

  1. Pisoni R, Wikstrom B, Elder S, et al. Pruritus in hemodialysis patients: international results from the dialysis outcomes and practice patterns study (DOPPS). Nephrol Dial Transplant. 2006;21:3495–3505

PII: S0272-6386(07)01604-6

doi:10.1053/j.ajkd.2007.12.008

Refers to article:

  • A Common Cause of Pruritus in Dialysis Patients

    Paul Jenkins
    American Journal of Kidney Diseases February 2008 (Vol. 51, Issue 2, Page 345)

American Journal of Kidney Diseases
Volume 51, Issue 2 , Pages 345-346, February 2008