American Journal of Kidney Diseases
Volume 51, Issue 4, Supplement 2 , Pages S38-S45 , April 2008

CKD and Cardiovascular Disease in Screened High-Risk Volunteer and General Populations: The Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004

  • Peter A. McCullough, MD, MPH, FACC

      Affiliations

    • Department of Medicine, Divisions of Cardiology, Nutrition, and Preventive Medicine, William Beaumont Hospital, Royal Oak, MI
    • Corresponding Author InformationAddress correspondence to Peter A. McCullough, MD, MPH, FACC, Divisions of Cardiology, Nutrition, and Preventive Medicine, William Beaumont Hospital, 4949 Coolidge Hwy, Royal Oak, MI 48073.
    • ,
  • Suying Li, PhD

      Affiliations

    • Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN
    • ,
  • Claudine T. Jurkovitz, MD

      Affiliations

    • Christiana Care Center for Outcomes Research, Christiana Care Health System, Newark, DE
    • ,
  • Lesley A. Stevens, MD

      Affiliations

    • Tufts-New England Medical Center, Boston, MA
    • ,
  • Changchun Wang, MS

      Affiliations

    • Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN
    • ,
  • Allan J. Collins, MD

      Affiliations

    • Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN
    • Charles R. Drew University of Medicine and Science and David Geffen School of Medicine, University of California, Los Angeles, CA
    • ,
  • Shu-Cheng Chen, MS

      Affiliations

    • Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, MN
    • ,
  • Keith C. Norris, MD
    • ,
  • Samy I. McFarlane, MD

      Affiliations

    • SUNY Downstate, Brooklyn, NY
    • ,
  • Bruce Johnson, MD

      Affiliations

    • KEEP Steering Committee, National Kidney Foundation, New York, NY
    • ,
  • Michael G. Shlipak, MD

      Affiliations

    • Veterans Administration Medical Center, San Francisco, CA
    • ,
  • Chamberlain I. Obialo, MD

      Affiliations

    • Renal Section, Department of Medicine, Morehouse School of Medicine, Atlanta, GA
    • ,
  • Wendy Weinstock Brown, MD

      Affiliations

    • Jesse Brown Veterans Administration Medical Center, Chicago, IL
    • ,
  • Joseph A. Vassalotti, MD

      Affiliations

    • National Kidney Foundation, New York, NY
    • Department of Medicine, Division of Nephrology, Mount Sinai School of Medicine, New York, NY
    • ,
  • Adam T. Whaley-Connell, MD

      Affiliations

    • University of Missouri-Columbia School of Medicine, Columbia, MO
    • ,
  • Kidney Early Evaluation Program Investigators

Received 16 November 2007 ,Accepted 27 December 2007.

  • Image Result

    Relative proportions of albumin-creatinine ratio (ACR) of 30 mg/g or greater, estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m2, and both as positive screening tests for chronic

    Relative proportions of albumin-creatinine ratio (ACR) of 30 mg/g or greater, estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m2, and both as positive screening tests for chronic kidney disease in the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004. P < 0.001 for eGFR and ACR trend. To convert eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, multiply by 0.01667.

  • Image Result
    Rates of self-reported myocardial infarction (MI) and stroke stratified by chronic kidney disease (CKD) status for the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examinat

    Rates of self-reported myocardial infarction (MI) and stroke stratified by chronic kidney disease (CKD) status for the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004. Death rates were 0.33 and 1.52/1,000 patient-years for non-CKD and CKD, respectively. NHANES 1999-2004 study population is 20 years and older. P < 0.001 for all pairwise comparisons.

 A list of author affiliations appears at the end of this article, as well as a list of the Kidney Early Evaluation Program Investigators.

PII: S0272-6386(08)00005-X

doi: 10.1053/j.ajkd.2007.12.017

American Journal of Kidney Diseases
Volume 51, Issue 4, Supplement 2 , Pages S38-S45 , April 2008

Article Tools

* Image Usage & Resolution