American Journal of Kidney Diseases
Volume 51, Issue 5 , Pages 829-833, May 2008

Severe Lactic Acidosis Associated With Juice of the Mangosteen Fruit Garcinia mangostana

  • Leslie P. Wong, MD

      Affiliations

    • Minor and James Medical, Seattle, WA
    • Department of Medicine, University of Washington School of Medicine, Seattle, WA
    • Corresponding Author InformationAddress correspondence to Leslie P. Wong, MD, Minor and James Medical, 515 Minor Ave, Ste 300, Seattle, WA 98104.
  • ,
  • Philip J. Klemmer, MD

      Affiliations

    • Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina School of Medicine, Chapel Hill, NC.

Received 3 October 2007; accepted 27 December 2007. published online 26 March 2008.

The tropical mangosteen fruit has long been prized in Southeast Asia for its traditional healing properties. Mangosteen fruit juice is now available in the United States and marketed for its purported health benefits. We describe a case of severe lactic acidosis associated with the use of mangosteen juice as a dietary supplement.

Index Words: Lactic acidosis, lactate, mangosteen, Garcinia mangostana, mitochondria

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 Originally published online as doi:10.1053/j.ajkd.2007.12.043 on March 27, 2008.

PII: S0272-6386(08)00172-8

doi:10.1053/j.ajkd.2007.12.043

American Journal of Kidney Diseases
Volume 51, Issue 5 , Pages 829-833, May 2008