American Journal of Kidney Diseases
Volume 51, Issue 5 , Pages 829-833 , May 2008

Severe Lactic Acidosis Associated With Juice of the Mangosteen Fruit Garcinia mangostana

  • Leslie P. Wong, MD

      Affiliations

    • Minor and James Medical, Seattle, WA
    • Department of Medicine, University of Washington School of Medicine, Seattle, WA
    • Corresponding Author InformationAddress correspondence to Leslie P. Wong, MD, Minor and James Medical, 515 Minor Ave, Ste 300, Seattle, WA 98104.
    • ,
  • Philip J. Klemmer, MD

      Affiliations

    • Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina School of Medicine, Chapel Hill, NC.

Received 3 October 2007 ,Accepted 27 December 2007.

References 

  1. Marcason W. What are the facts and myths about mangosteen?. J Am Diet Assoc. 2006;106:986
  2. Sato A, Fujiwara H, Hisae O, et al. Alpha-mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells. J Pharmacol Sci. 2004;95:33–40
  3. Matsumoto K, Akao Y, Kobayashi E, et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod. 2003;66:1124–1127
  4. Matsumoto K, Akao Y, Yi H, et al. Preferential target is mitochondria in alpha-mangostin-induced apoptosis in human leukemia HL60 cells. Bioorg Med Chem. 2004;12:5799–5806
  5. Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002;63:73–79
  6. McKenzie R, Fried MW, Sallie R, et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med. 1995;333:1099–1105
  7. Claessens YE, Chiche JD, Mira JP, Cariou A. Bench-to-bedside review: Severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors. Crit Care. 2003;7:226–232
  8. Cote HC, Brumme ZL, Craib KJ, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N Engl J Med. 2002;346:811–820
  9. Chan TY, Tam HP, Lai CK, Chan AY. A multidisciplinary approach to the toxicologic problems associated with the use of herbal medicines. Ther Drug Monit. 2005;27:53–57
  10. Neto MM, Rubl F, Netto JC. Intoxication by the star fruit (Averrhoa carambola) in six dialysis patients?. (preliminary report) Nephrol Dial Transplant. 1998;13:570–572
  11. Kaplan LJ, Frangos S. Clinical review: Acid-base abnormalities in the intensive care unit—Part II. Crit Care. 2005;9:198–203
  12. Meregalli A, Oliveira RP, Friedman G. Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients. Crit Care. 2004;8:R60–R65
  13. Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med. 2007;33:1892–1899
  14. Levy B, Sadoune LO, Gelot AM, Papiris S, Roussos C. Evolution of lactate/pyruvate and arterial ketone body ratios in the early course of catecholamine-treated septic shock. Crit Care Med. 2000;28:114–119
  15. Rose BD, Post TW. Causes of lactic acidosis. 2007;UpToDate version 15.2, Waltham, MA
  16. Robinson BH. Lactic acidemia and mitochondrial disease. Mol Genet Metab. 2006;89:3–13
  17. Narins RG, Cohen JJ. Bicarbonate therapy for organic acidosis: The case for its continued use. Ann Intern Med. 1987;106:615–618
  18. Orchard CH, Kentish JC. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol. 1990;258:C967–C981
  19. Cooper DJ, Walley KR, Wiggs BR, Russell JA. Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis (A prospective, controlled clinical study). Ann Intern Med. 1990;112:492–498
  20. Chang CT, Chen YC, Fang JT, Huang CC. Metformin-associated lactic acidosis: Case reports and literature review. J Nephrol. 2002;15:398–402
  21. Adams GR, Vaziri ND. Skeletal muscle dysfunction in chronic renal failure: Effects of exercise. Am J Physiol Renal Physiol. 2006;290:F753–F761
  22. Nisoli E, Clementi E, Carruba MO, Moncado S. Defective mitochondrial biogenesis: A hallmark of the high cardiovascular risk in the metabolic syndrome?. Circ Res. 2007;100:795–806
  23. Marrades RM, Roca J, Campistol JM, et al. Effects of erythropoietin on muscle O2 transport during exercise in patients with chronic renal failure. J Clin Invest. 1996;97:2092–2100
  24. Rodrigo GJ, Rodrigo C. Elevated plasma lactate level associated with high dose inhaled albuterol therapy in acute severe asthma. Emerg Med J. 2005;22:404–408
  25. Stratakos G, Kalomenidis J, Routsi C, et al. Transient lactic acidosis as a side effect of inhaled salbutamol. Chest. 2002;122:385–386
  26. Manthous CA. Lactic acidosis in status asthmaticus: Three cases and review of the literature. Chest. 2001;119:1599–1602
  27. Animal and Plant Health Inspection Service, United States Department of Agriculture. Importation of fruit from Thailand. Fed Regist. 2007;72:34163–34176

 Originally published online as doi:10.1053/j.ajkd.2007.12.043 on March 27, 2008.

PII: S0272-6386(08)00172-8

doi: 10.1053/j.ajkd.2007.12.043

American Journal of Kidney Diseases
Volume 51, Issue 5 , Pages 829-833 , May 2008

Article Tools

* Image Usage & Resolution