American Journal of Kidney Diseases
Volume 51, Issue 6 , Pages 875-876 , June 2008

The Renal Fanconi Syndromes: The Proper Study of Mankind is Man

  • Anthony G. Norden, MBBS, PhD

      Affiliations

    • Corresponding Author InformationAddress correspondence to Anthony G. Norden, MD, Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Road, Box 232, Cambridge, United Kingdom CB2 2QR.

References 

  1. Bergeron M, Gougoux A, Noel J, Parent L. The Renal Fanconi Syndrome. In:  Scriver CR,  Beaudet AL,  Sly WS,  Valle D,  Childs B,  Kizler KW,  Vogelstein B editor. The Metabolic and Molecular Basis of Inherited Disease. (ed 8). New York, NY: McGraw-Hill; 2001;p. 5023–5038
  2. Wilmer MJ, Christensen EI, van den Heuvel LP, Monnens LA, Levtchenko EN. Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. Am J Kidney Dis. 2008;51:893–903
  3. Devuyst O, Jouret F, Auzanneau C, Courtoy PJ. Chloride channels and endocytosis: new insights from Dent's disease and ClC-5 knockout mice. Nephron Physiol. 2005;99:69–73
  4. Guggino SE. Mechanisms of disease: what can mouse models tell us about the molecular processes underlying Dent disease?. Nat Clin Pract Nephrol. 2007;3:449–455
  5. Norden AG, Lapsley M, Igarashi T, et al. Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. J Am Soc Nephrol. 2002;13:125–133
  6. Santo Y, Hirai H, Shima M, et al. Examination of megalin in renal tubular epithelium from patients with Dent disease. Pediatr Nephrol. 2004;19:612–615
  7. Russo LM, Sandoval RM, McKee M, et al. The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007;71:504–513

PII: S0272-6386(08)00742-7

doi: 10.1053/j.ajkd.2008.04.003

American Journal of Kidney Diseases
Volume 51, Issue 6 , Pages 875-876 , June 2008