American Journal of Kidney Diseases
Volume 54, Issue 1 , Pages 122-126 , July 2009

BK Virus Nephropathy Due to KOM-3 Strain

  • Gavin S.W. Chan, FRCPA

      Affiliations

    • Department of Pathology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King
    • Corresponding Author InformationAddress correspondence to Gavin S.W. Chan, FRCPA, Department of Pathology, Queen Mary Hospital, Hong Kong
    • ,
  • Hoi Wah Tsoi, MPhil

      Affiliations

    • Department of Microbiology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King
    • ,
  • Samson S.Y. Wong, MRCPath, DTMH

      Affiliations

    • Department of Microbiology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King
    • ,
  • Chiu Leong Li

      Affiliations

    • Department of Nephrology, Centro Hospitalar Conde De S Januario, Macau
    • ,
  • Herman Tse, MBBS

      Affiliations

    • Department of Microbiology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King
    • ,
  • Kuok Un I

      Affiliations

    • Department of Nephrology, Centro Hospitalar Conde De S Januario, Macau
    • ,
  • Kwok Yung Yuen, MD, FRCS, FRCPath

      Affiliations

    • Department of Microbiology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King
    • ,
  • Kwok Wah Chan, FRCPath

      Affiliations

    • Department of Pathology, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong King

Received 11 July 2008 ,Accepted 17 September 2008.

References 

  1. Gardner S, Field A, Coleman D, Hulme B. New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet. 1971;1:1253–1257
  2. Purighalla R, Shapiro R, McCauley J, Randhawa P. BK virus infection in a kidney allograft diagnosed by needle biopsy. Am J Kidney Dis. 1995;26:671–673
  3. Fishman JA. BK virus nephropathy—Polyomavirus adding insult to injury. N Engl J Med. 2002;347:527–530
  4. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med. 2002;347:488–496
  5. Howell DN, Smith SR, Butterly DW, et al. Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation. 1999;68:1279–1288
  6. Rocha PN, Plumb TJ, Miller SE, Howell DN, Smith SR. Risk factors for BK polyomavirus nephritis in renal allograft recipients. Clin Transplant. 2004;18:456–462
  7. Hodur DM, Mandelbrot D. Immunosuppression and BKV nephropathy. N Engl J Med. 2002;347:2079–2080(author reply)
  8. Marshall J, Smith AE, Cheng SH. Monoclonal antibody specific for BK virus large T antigen allows discrimination among the different papovaviral large T antigens. Oncogene. 1991;6:1673–1676
  9. Shinohara T, Matsuda M, Cheng SH, Marshall J, Fujita M, Nagashima K. BK virus infection of the human urinary tract. J Med Virol. 1993;41:301–305
  10. Solez K, Axelsen RA, Benediktsson H, et al. International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology. Kidney Int. 1993;44:411–422
  11. Takasaka T, Goya N, Tokumoto T, et al. Subtypes of BK virus prevalent in Japan and variation in their transcriptional control region. J Gen Virol. 2004;85:2821–2827
  12. Smith RD, Galla JH, Skahan K, et al. Tubulointerstitial nephritis due to a mutant polyomavirus BK virus strain, BKV(Cin), causing end-stage renal disease. J Clin Microbiol. 1998;36:1660–1665
  13. Baksh FK, Finkelstein SD, Swalsky PA, Stoner GL, Ryschkewitsch CF, Randhawa P. Molecular genotyping of BK and JC viruses in human polyomavirus-associated interstitial nephritis after renal transplantation. Am J Kidney Dis. 2001;38:354–365
  14. Nishimoto Y, Takasaka T, Hasegawa M, et al. Evolution of BK virus based on complete genome data. J Mol Evol. 2006;63:341–352
  15. Zhong S, Yogo Y, Ogawa Y, et al. Even distribution of BK polyomavirus subtypes and subgroups in the Japanese Archipelago. Arch Virol. 2007;152:1613–1621
  16. Gosert R, Rinaldo CH, Funk GA, et al. Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathology. J Exp Med. 2008;205:841–852

 Originally published online as doi: 10.1053/j.ajkd.2008.09.014 on November 20, 2008.

PII: S0272-6386(08)01407-8

doi: 10.1053/j.ajkd.2008.09.014

American Journal of Kidney Diseases
Volume 54, Issue 1 , Pages 122-126 , July 2009

Article Tools

* Image Usage & Resolution