American Journal of Kidney Diseases
Volume 53, Issue 4 , Pages 628-637 , April 2009

Treatment of Idiopathic Retroperitoneal Fibrosis With Colchicine and Steroids: A Case Series

  • Jorge Vega, MD

      Affiliations

    • Departamento de Medicina Interna, Sección Nefrología, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • Departamento de Medicina, Facultad de Medicina, Universidad de Valparaíso, Valparaíso, Chile
    • Corresponding Author InformationAddress correspondence to Jorge Vega, MD, 5 Norte 1035, Viña del Mar, Chile
    • ,
  • Helmuth Goecke, MD

      Affiliations

    • Departamento de Medicina Interna, Sección Nefrología, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • Departamento de Medicina, Facultad de Medicina, Universidad de Valparaíso, Valparaíso, Chile
    • ,
  • Héctor Tapia, MD

      Affiliations

    • Departamento de Medicina Interna, Sección Nefrología, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • ,
  • Eduardo Labarca, MD

      Affiliations

    • Departamento de Cirugía, Sección de Cirugía Vascular, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • ,
  • Mario Santamarina, MD

      Affiliations

    • Departamento de Radiología, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • ,
  • Gonzalo Martínez, MD

      Affiliations

    • Departamento de Medicina Interna, Sección Nefrología, Hospital Naval Almirante Nef, Viña del Mar, Chile
    • Departamento de Medicina, Facultad de Medicina, Universidad de Valparaíso, Valparaíso, Chile

Received 15 July 2008 ,Accepted 18 September 2008.

References 

  1. Vaglio A, Salvarani C, Buzio C. Retroperitoneal fibrosis. Lancet. 2006;367:241-225
  2. Van Bommel E. Retroperitoneal fibrosis. Neth J Med. 2002;60:231–242
  3. Albarran J. Retention renale para periureterite: Liberation externe de l'uretere. Assoc Fr Urol. 1905;9:511–517
  4. Greco P, Vaglio A, Manenti L, et al. Idiopathic retroperitoneal fibrosis. G Ital Nefrol. 2004;21:132–138
  5. Baker L, Mallinson W, Gregory M, et al. Idiopathic retroperitoneal fibrosis (A retrospective analysis of 60 cases). Br J Urol. 1987;60:497–503
  6. Corradi D, Maestri R, Palmisano A, et al. Idiopathic retroperitoneal fibrosis: Clinicopathologic features and differential diagnosis. Kidney Int. 2007;72:742–753
  7. Kamisawa T, Okamoto A. IgG4-related sclerosing disease. World J Gastroenterol. 2008;14:3948–3955
  8. Neild G, Rodriguez-Justo M, Wall C, Connolly J. Hyper-IgG4 disease: Report and characterisation of a new disease. BMC Med. 2006;4:23
  9. Swartz R, Lake A, Roberts W, Faerber G, Wolf J. Idiopathic retroperitoneal fibrosis: A role for mycophenolate mofetil. Clin Nephrol. 2008;69:260–268
  10. Marcolongo R, Tavolini I, Laveder F, et al. Immunosuppressive therapy for idiopathic retroperitoneal fibrosis: A retrospective analysis of 26 cases. Am J Med. 2004;116:194–197
  11. Vaglio A, Corradi D, Manenti L, Ferreti S, Garini G, Buzio C. Evidence of autoimmunity in chronic periaortitis: A prospective study. Am J Med. 2003;114:454–462
  12. Warnatz K, Keskin A, Uhl M, et al. Immunosuppressive treatment of chronic periaortitis: A retrospective study of 20 patients with chronic periaortitis and review of the literature. Ann Rheum Dis. 2005;64:828–833
  13. Van Bommel , Hendricksz T, Huiskes A, Zeegers A. Brief communication: Tamoxifen therapy for nonmalignant retroperitoneal fibrosis. Ann Intern Med. 2006;144:101–106
  14. Cerquaglia C, Diaco M, Nucera G, La Regina M, Montalto M, Manna R. Pharmacological and clinical basis of treatment of familial Mediterranean fever with colchicine or analogues: An update. Curr Drug Targets Inflamm Allergy. 2005;4:117–124
  15. Niel E, Schermann J. Colchicine today. Joint Bone Spine. 2006;73:672–678
  16. Morgan T, Weiss D, Nemchausky B, et al. Colchicine treatment of alcoholic cirrhosis: A randomized, placebo-controlled clinical trial of patient survival. Gastroenterology. 2005;128:882–890
  17. Rennard S, Bitterman P, Ozaki T, Rom W, Crystal R. Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro (The basis of a possible therapeutic approach of the fibrotic disorders). Am Rev Respir Dis. 1988;137:181–185
  18. Peterson T, Isbrucker R, Hooper M. In vitro effect of platelet-derived growth factor on fibroproliferation and effect of cytokine antagonists. Immunopharmacology. 1994;28:259–270
  19. Huang W, Sun H, Pan X, et al. Effects of colchicine on synthesis and excretion of cytokines and extracellular matrix by human renal fibroblasts. Zhonghua Er Ke Za Zhi. 2004;42:524–528
  20. Entzian P, Schlaak M, Sitzer U, Bufe A, Acil Y, Zabel P. Antiinflammatory and antifibrotic properties of colchicine: Implications for idiopathic pulmonary fibrosis. Lung. 1997;175:41–51
  21. Ben-Chetrit E, Levy M. Colchicine: 1998 Update. Semin Arthritis Rheum. 1998;28:48–59
  22. Lange U, Schumann C, Schmidt K. Current aspects of colchicine therapy—Classical indications and new therapeutic uses. Eur J Med Res. 2001;6:150–160
  23. Li C, Yang C, Ahn H, et al. Colchicine decreases apoptotic cell death in chronic cyclosporine nephrotoxicity. J Lab Clin Med. 2002;139:364–371
  24. Vaglio A, Greco P, Corradi D, et al. Autoimmune aspects of chronic periaortitis. Autoimmun Rev. 2006;5:458–464
  25. Khan A. Retroperitoneal fibrosis. www.emedicine.com/radio/topic605.htmAccessed April 17, 2007
  26. Maillart E, Laueriere L, Kassis S, et al. Is there an evidence-based management of idiopathic retroperitoneal fibrosis?. Rev Med Interne. 2006;27:854–857
  27. Marzano A, Trapani A, Leone N, Actis G, Rizzetto M. Treatment of idiopathic retroperitoneal fibrosis using cyclosporine. Ann Rheum Dis. 2001;60:427–428
  28. Grotz W, Von Zedtwitz , Andre M, Schollmeyer P. Treatment of retroperitoneal fibrosis by mycophenolate mofetil and corticosteroids. Lancet. 1998;352:1195
  29. Moroni G, Gallelli B, Banfi G, Sandri S, Messa P, Ponticelli C. Long-term outcome of idiopathic retroperitoneal fibrosis treated with surgical and/or medical approaches. Nephrol Dial Transplant. 2006;21:2485–2490
  30. Castilho L, Mitre A, Izuka F, Fugita O, Colombo J, Arap S. Laparoscopic treatment of retroperitoneal fibrosis: Report of two cases and review of the literature. Rev Hosp Clin Fac Med Sao Paulo. 2000;55:69–76
  31. Kershenobich D, Uribe M, Suarez G, Mata J, Perez-Tamayo R, Rojkind M. Treatment of cirrhosis with colchicine (A double-blind randomized trial). Gastroenterology. 1979;77:532–536
  32. Kershenobich D, Rojkind M, Quiroga A, Alcocer-Varela J. Effect of colchicine on lymphocyte and monocyte function and its relation to fibroblast proliferation in primary biliary cirrhosis. Hepatology. 1990;11:205–209
  33. Lindor K, Wiesner R, Colwell L, Steiner B, Beaver S, Larusso N. The combination of prednisone and colchicine in patient with primary sclerosing cholangitis. Am J Gastroenterol. 1991;86:57–61
  34. Undurraga A, Meneses M, Sabbagh E, Oyarzun M. Treatment of idiopathic pulmonary fibrosis with colchicine. Rev Med Chil. 1998;126:1345–1353
  35. Horton K, Lawler L, Fishman E. CT findings in sclerosing mesenteritis (panniculitis): Spectrum of disease. Radiographics. 2003;23:1561–1567
  36. Rambaldi A, Gluud C. Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. Cochrane Database Syst Rev. 2005;2:CD002148
  37. Rojkind M, Kershenobich D. Effect of colchicine on collagen, albumin and transferrin synthesis by cirrhotic rat liver slices. Biochim Biophys Acta. 1975;378:415–423
  38. Kinami Y, Sakata N, Takata M. Effects of antifibrotic substances on pancreatic fibrosis following acute necrotizing pancreatitis. Gastroenterol Jpn. 1986;21:499–507
  39. Shahar E, Keidar I, Hertzeg E, Barzilay Z. Effectiveness of vitamin E and colchicine in amelioration of paraquat lung injuries using an experimental model. Isr Med Sci. 1989;25:92–94
  40. Scheel J, Piccini J, Rahman M, Lawler L, Jarrett T. Combined prednisone and mycophenolate mofetil treatment for retroperitoneal fibrosis. J Urol. 2007;178:140–144
  41. Van Bommel E, Siemes C, Hak L, Van Der Veer S, Hendriksz T. Long-term renal and patient outcome in idiopathic retroperitoneal fibrosis treated with prednisone. Am J Kidney Dis. 2007;49:615–625

 Originally published online as doi:10.1053/j.ajkd.2008.09.025 on January 5, 2009.

PII: S0272-6386(08)01612-0

doi: 10.1053/j.ajkd.2008.09.025

American Journal of Kidney Diseases
Volume 53, Issue 4 , Pages 628-637 , April 2009

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