American Journal of Kidney Diseases
Volume 54, Issue 1 , Pages 154-158 , July 2009

Subacute Allograft Failure With Dysuria and Hematuria in a Kidney Transplant Recipient

  • Ariana Gaspert, MD

      Affiliations

    • Department of Pathology, University Hospital, Zürich, Switzerland
    • ,
  • Beatrice Lüthi, MD

      Affiliations

    • Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Zürich, Switzerland
    • ,
  • Nicolas J. Mueller, MD

      Affiliations

    • Clinic of Nephrology, University Hospital, Zürich, Switzerland
    • ,
  • Walter Bossart, MD

      Affiliations

    • Institute of Virology, University Hospital, Zürich, Switzerland
    • ,
  • Albert Heim, MD

      Affiliations

    • Institute of Virology, Medizinische Hochschule, Hannover, Germany
    • ,
  • Rudolf P. Wüthrich, MD

      Affiliations

    • Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Zürich, Switzerland
    • ,
  • Thomas Fehr, MD

      Affiliations

    • Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Zürich, Switzerland
    • Corresponding Author InformationAddress correspondence to Thomas Fehr, MD, Clinic of Nephrology, University Hospital, Rämistrasse 100, CH-8091 Zürich, Switzerland

Received 11 July 2008 ,Accepted 5 November 2008.

References 

  1. Madisch I, Wolfel R, Harste G, Pommer H, Heim A. Molecular identification of adenovirus sequences: A rapid scheme for early typing of human adenoviruses in diagnostic samples of immunocompetent and immunodeficient patients. J Med Virol. 2006;78:1210–1217
  2. Humar A, Kumar D, Mazzulli T, et al. A surveillance study of adenovirus infection in adult solid organ transplant recipients. Am J Transplant. 2005;5:2555–2559
  3. Hierholzer JC. Adenoviruses in the immunocompromised host. Clin Microbiol Rev. 1992;5:262–274
  4. Mathur SC, Squiers EC, Tatum AH, et al. Adenovirus infection of the renal allograft with sparing of pancreas graft function in the recipient of a combined kidney-pancreas transplant. Transplantation. 1998;65:138–141
  5. Koga S, Shindo K, Matsuya F, Hori T, Kanda S, Kanetake H. Acute hemorrhagic cystitis caused by adenovirus following renal transplantation: Review of the literature. J Urol. 1993;149:838–839
  6. Asim M, Chong-Lopez A, Nickeleit V. Adenovirus infection of a renal allograft. Am J Kidney Dis. 2003;41:696–701
  7. Alsaad KO, Tobar A, Belanger E, Ahmad M, Cattran DC, Herzenberg AM. Late-onset acute haemorrhagic necrotizing granulomatous adenovirus tubulointerstitial nephritis in a renal allograft. Nephrol Dial Transplant. 2007;22:1257–1260
  8. Teague MW, Glick AD, Fogo AB. Adenovirus infection of the kidney: Mass formation in a patient with Hodgkin's disease. Am J Kidney Dis. 1991;18:499–502
  9. Lim AK, Parsons S, Ierino F. Adenovirus tubulointerstitial nephritis presenting as a renal allograft space occupying lesion. Am J Transplant. 2005;5:2062–2066
  10. Bijol V, Mendez GP, Nose V, Rennke HG. Granulomatous interstitial nephritis: A clinicopathologic study of 46 cases from a single institution. Int J Surg Pathol. 2006;14:57–63
  11. Nasr SH, Koscica J, Markowitz GS, D'Agati VD. Granulomatous interstitial nephritis. Am J Kidney Dis. 2003;41:714–719
  12. Pham TT, Burchette JL, Hale LP. Fatal disseminated adenovirus infections in immunocompromised patients. Am J Clin Pathol. 2003;120:575–583
  13. Friedrichs N, Eis-Hubinger AM, Heim A, Platen E, Zhou H, Buettner R. Acute adenoviral infection of a graft by serotype 35 following renal transplantation. Pathol Res Pract. 2003;199:565–570
  14. Ljungman P, Ribaud P, Eyrich M, et al. Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: A survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant. 2003;31:481–486
  15. Wright NG, Morrison WI, Thompson H, Cornwell HJ. Mesangial localization of immune complexes in experimental canine adenovirus glomerulonephritis. Br J Exp Pathol. 1974;55:458–465
  16. Smith MC, Cooke JH, Zimmerman DM, et al. Asymptomatic glomerulonephritis after nonstreptococcal upper respiratory infections. Ann Intern Med. 1979;91:697–702

 Originally published online as doi: 10.1053/j.ajkd.2008.11.008 on January 5, 2009.

PII: S0272-6386(08)01622-3

doi: 10.1053/j.ajkd.2008.11.008

American Journal of Kidney Diseases
Volume 54, Issue 1 , Pages 154-158 , July 2009

Article Tools

* Image Usage & Resolution