American Journal of Kidney Diseases
Volume 53, Issue 4 , Pages 569-571 , April 2009

Ironing Out the Pathogenesis of Acute Kidney Injury

  • Sangeeta Hingorani, MD

      Affiliations

    • Seattle Children's Hospital, Seattle, Washington
    • ,
  • Bruce A. Molitoris, MD

      Affiliations

    • Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • Jonathan Himmelfarb, MD

      Affiliations

    • University of Washington School of Medicine, Seattle, Washington
    • Corresponding Author InformationAddress correspondence to Jonathan Himmelfarb, MD, Division of Nephrology, University of Washington School of Medicine, Seattle, WA

References 

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  2. Ishani A, Xue JL, Himmelfarb J, et al. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol. 2009;20:223–228
  3. Molitoris BA, Melnikov VY, Okusa MD, Himmelfarb J. Technology insight: Biomarker development in acute kidney injury—What can we anticipate?. Nat Clin Pract Nephrol. 2008;4:154–165
  4. Beddhu S, Samore MH, Roberts MS, Stoddard GJ, Pappas LM, Cheung AK. Creatinine production, nutrition, and glomerular filtration rate estimation. J Am Soc Nephrol. 2003;14:1000–1005
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  8. Ho J, Lucy M, Krokhin O, et al. Mass spectrometry–based protemic analysis of urine in acute kidney injury following cardiopulmonary bypass: A nested case-control study. Am J Kidney Dis. 2009;53:584–595
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  13. Kulaksiz H, Theilig F, Bachmann S, et al. The iron-regulatory peptide hormone hepcidin: Expression and cellular localization in the mammalian kidney. J Endocrinol. 2005;184:361–370
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  15. Babitt JL, Huang FW, Wrighting DM, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38:531–539
  16. Meyron-Holtz EG, Ghosh MC, Iwai K, et al. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. EMBO J. 2004;23:386–395
  17. Zhang D, Meyron-Holtz E, Rouault TA. Renal iron metabolism: Transferrin iron delivery and the role of iron regulatory proteins. J Am Soc Nephrol. 2007;18:401–406
  18. Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. Immunoassay for human serum hepcidin. Blood. 2008;112:4292–4297

PII: S0272-6386(09)00029-8

doi: 10.1053/j.ajkd.2009.01.002

American Journal of Kidney Diseases
Volume 53, Issue 4 , Pages 569-571 , April 2009

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