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Volume 53, Issue 4 , Pages 681-688 , April 2009

CKD as an Underrecognized Threat to Patient Safety

Jeffrey C. Fink, MD
- Department of Medicine, University of Maryland School of Pharmacy, Baltimore, MD
- Department of Epidemiology, University of Maryland School of Pharmacy, Baltimore, MD
- Address correspondence to Jeffrey C. Fink, MD, Rm N3W143, 22 S Greene St, University of Maryland School of Medicine, Baltimore, MD 21201
Jeanine Brown, MS
- Department of Medicine, University of Maryland School of Pharmacy, Baltimore, MD
Van Doren Hsu, PharmD
- Department of Pharmaceutical Research Computing, University of Maryland School of Pharmacy, Baltimore, MD
Stephen L. Seliger, MD
- Department of Medicine, University of Maryland School of Pharmacy, Baltimore, MD
- Department of Epidemiology, University of Maryland School of Pharmacy, Baltimore, MD
Loreen Walker, BS
- Department of Pharmaceutical Research Computing, University of Maryland School of Pharmacy, Baltimore, MD
Min Zhan, PhD
- Department of Epidemiology, University of Maryland School of Pharmacy, Baltimore, MD

Received 8 October 2008 ,Accepted 22 December 2008.

A theoretical patient with chronic kidney disease is subject to several events that might be classified as preventable and related to patient safety. These events contribute to an accelerated rate of

A theoretical patient with chronic kidney disease is subject to several events that might be classified as preventable and related to patient safety. These events contribute to an accelerated rate of kidney function decay. Abbreviations: ACE, angiotensin-converting enzyme (inhibitor); ESRD, end-stage renal disease; GFR, glomerular filtration rate; NSAID, nonsteroidal anti-inflammatory drug.
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The Donabedian structure-process-outcome framework13 applied to the chronic kidney disease (CKD) model. The model proposes a causal link between the disease-specific structural deficit of poor disease

The Donabedian structure-process-outcome framework¹³ applied to the chronic kidney disease (CKD) model. The model proposes a causal link between the disease-specific structural deficit of poor disease recognition and adverse disease outcomes, mediated through several candidate disease-specific safety measures. Abbreviations: AHRQ, Agency for Healthcare Research and Quality; AKI, acute kidney injury; ER, emergency room; ESRD, end-stage renal disease; NSAID, nonsteroidal anti-inflammatory drug.
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