American Journal of Kidney Diseases
Volume 54, Issue 3 , Pages 468-477 , September 2009

Cerebrovascular Disease Incidence, Characteristics, and Outcomes in Patients Initiating Dialysis: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study

  • Stephen M. Sozio, MD, MHS

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
    • Corresponding Author InformationAddress correspondence to Stephen M. Sozio, MD, MHS, Johns Hopkins University School of Medicine, Division of Nephrology, 1830 E Monument St, Ste 416; Baltimore, MD 21205
  • ,
  • Paige A. Armstrong, MHS

      Affiliations

    • University of Connecticut School of Medicine, Farmington, CT
  • ,
  • Josef Coresh, MD, PhD

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
    • Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
  • ,
  • Bernard G. Jaar, MD, MPH

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
    • Nephrology Center of Maryland, Baltimore, MD
  • ,
  • Nancy E. Fink, MPH

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
  • ,
  • Laura C. Plantinga, ScM

      Affiliations

    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
  • ,
  • Neil R. Powe, MD, MPH, MBA

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
  • ,
  • Rulan S. Parekh, MD, MS

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    • Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD
    • Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD

Received 10 September 2008 ,Accepted 14 January 2009.

  • Image Result

    Cerebrovascular event classification in 1,041 incident dialysis patients. The number of each cerebrovascular event, including recurrent events, is shown. Event types were determined from International

    Cerebrovascular event classification in 1,041 incident dialysis patients. The number of each cerebrovascular event, including recurrent events, is shown. Event types were determined from International Classification of Diseases, Ninth Revision codes and chart abstraction. Ischemic stroke subtypes were defined using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification system by 2 abstractors. *Of 165 patients, 35 had repeated events. †No statistically significant differences from nonabstracted patients with regard to demographics, comorbid conditions, or baseline laboratory results. Abbreviations: CEA, carotid endarterectomy; USRDS, US Renal Data System.

  • Image Result
    Cumulative incidence of cerebrovascular events in incident dialysis patients accounts for the competing risk of death from causes other than stroke. Abbreviation: CEA, carotid endarterectomy.

    Cumulative incidence of cerebrovascular events in incident dialysis patients accounts for the competing risk of death from causes other than stroke. Abbreviation: CEA, carotid endarterectomy.

 Originally published online as doi: 10.1053/j.ajkd.2009.01.261 on April 20, 2009.

 Because the Editor-in-Chief recused himself from consideration of this manuscript, the Deputy Editor (Daniel E. Weiner, MD, MS) served as Acting Editor-in-Chief. Details of the journal's procedures for potential editor conflicts are given in the Editorial Policies section of the AJKD website.

PII: S0272-6386(09)00432-6

doi: 10.1053/j.ajkd.2009.01.261

American Journal of Kidney Diseases
Volume 54, Issue 3 , Pages 468-477 , September 2009