American Journal of Kidney Diseases
Volume 54, Issue 2 , Pages 278-288 , August 2009

Comparison of GFR Measurements Assessed From Single Versus Multiple Samples

  • Nicholas J. Bird, PhD

      Affiliations

    • Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • Christina Peters, MSc

      Affiliations

    • Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • A. Robert Michell, PhD

      Affiliations

    • William Harvey Research Institute, Department of Biochemical Pharmacology, St Bartholomew's Medical School, London, UK
    • ,
  • A. Michael Peters, MD

      Affiliations

    • Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK
    • Corresponding Author InformationAddress correspondence to A. Michael Peters, MD, Audrey Emerton Bldg, Royal Sussex County Hospital, Eastern Rd, Brighton BN2 5BE, UK

Received 20 August 2008 ,Accepted 20 March 2009.

References 

  1. Chatterton BE. Limitations of the single sample tracer method for determining glomerular filtration rate. Br J Radiol. 1978;51:981–985
  2. Constable AR, Hussein MM, Albrecht MP, Thompson FD, Philalithis PE, Joekes AM. Single sample estimates of renal clearances. Br J Urol. 1979;51:84–87
  3. Rehling M, Rabøl A. Measurement of glomerular filtration rate in adults: Accuracy of five single-sample plasma clearance methods. Clin Physiol. 1989;9:171–182
  4. Tauxe WN. Determination of glomerular filtration rate by single-plasma sampling technique following injection of radioiodinated diatrizoate. J Nucl Med. 1986;27:45–50
  5. Waller DG, Keast CM, Fleming JS, Ackery DM. Measurement of glomerular filtration rate with technetium-99m DTPA: Comparison of plasma clearance techniques. J Nucl Med. 1987;28:372–377
  6. Tepe PG, Tauxe WN, Bagchi A, Rezende P, Krishnaiah PR. Comparison of measurement of glomerular filtration rate by single sample, plasma disappearance slope/intercept and other methods. Eur J Nucl Med. 1987;13:28–31
  7. Sterner G, Frennby B, Hultberg B, Almen T. Iohexol clearance for GFR-determination in renal failure—Single or multiple plasma sampling?. Nephrol Dial Transplant. 1996;11:521–525
  8. Rocco MV, Buckalew VM, Moore LC, Shihabi ZK. Measurement of glomerular filtration rate using nonradioactive iohexol: Comparison of two one-compartment models. Am J Nephrol. 1996;16:138–143
  9. Li Y, Lee HB, Blaufox MD. Single-sample methods to measure GFR with technetium-99m-DTPA. J Nucl Med. 1997;38:1290–1295
  10. Gaspari F, Guerini E, Perico N, Mosconi L, Ruggenenti P, Remuzzi G. Glomerular filtration rate determined from a single plasma sample after intravenous iohexol injection: Is it reliable?. J Am Soc Nephrol. 1996;7:2689–2693
  11. Mulligan JS, Blue PW, Hasbargen JA. Methods for measuring GFR with technetium-99m-DTPA: An analysis of several common methods. J Nucl Med. 1990;31:1211–1219
  12. Martensson J, Groth S, Rehling M, Gref M. Chromium-51-EDTA clearance in adults with a single-plasma sample of plasma clearance of 99mTc diethylenetriaminepentaaceticacid. J Nucl Med. 1998;39:2131–2137
  13. Russell CD, Bischoff PG, Kontzen FN, et al. Measurement of glomerular filtration rate: Single injection plasma clearance method without urine collection. J Nucl Med. 1985;26:1243–1247
  14. Rydstrom M, Tengstrom B, Cederquist I, Ahlmen J. Measurement of glomerular filtration rate by single-injection, single-sample techniques, using 51Cr-EDTA or iohexol. Scand J Urol Nephrol. 1995;9:135–139
  15. Eriksson CG, Kallner A. Glomerular filtration rate: A comparison between Cr-EDTA clearance and a single sample technique with a non-ionic contrast agent. Clin Biochem. 1991;24:261–264
  16. Lundqvist S, Hietala SO, Groth S, Sjödin JG. Evaluation of single sample clearance calculations in 902 patients (A comparison of multiple and single sample techniques). Acta Radiol. 1997;38:68–72
  17. Gref M, Karp K. GFR determination in adults with a single-sample iohexol plasma clearance method based on the mean sojourn time. Nephrol Dial Transplant. 2007;22:3166–3173
  18. Cousins C, Skehan SJ, Rolph S, et al. Comparative microvascular exchange kinetics of [77Br]bromide and 99mTc-DTPA in humans. Eur J Nucl Med. 2002;29:655–662
  19. Bird NJ, Peters C, Miichell AR, Peters AM. Suitability of a simplified technique based on iohexol for de-centralised measurement of glomerular filtration rate. Scand J Urol Nephrol. 2008;42:472–480
  20. Bird NJ, Peters C, Michell AR, Peters AM. Reproducibilities and responses to food intake of GFR measured with chromium-51-EDTA and iohexol simultaneously and independently in normal subjects. Nephrol Dial Transplant. 2008;23:1902–1909
  21. Du Bois D, Du Bois EF. A formula to estimate the approximate surface area if height and weight are known. Arch Intern Med. 1916;17:863
  22. Jacobsson L. A method for the calculation of renal clearance based on a single plasma sample. Clin Physiol. 1983;3:297–305
  23. Altman DG. Practical Statistics for Medical Research. In: London, UK: Chapman & Hall; 1991;p. 269–270
  24. Brandstrom E, Grzegorczyk A, Jacobsson L, Friberg P, Lindahl A, Aurell M. GFR measurement with iohexol and 51Cr-EDTA (A comparison of the two favoured GFR markers in Europe). Nephrol Dial Transplant. 1998;13:1176–1182
  25. Brown SC, O'Reilly PH. Iohexol clearance for the determination of glomerular filtration rate in clinical practice: Evidence for a new gold standard. J Urol. 1991;146:675–679
  26. Gaspari F, Perico N, Ruggenenti P, et al. Plasma clearance of non-radioactive iohexol as a measure of glomerular filtration rate. J Am Soc Nephrol. 1995;6:257–263
  27. James TJ, Lewis AV, Tan GD, Altmann P, Taylor RP, Levy JC. Validity of simplified protocols to estimate glomerular filtration rate using iohexol clearance. Ann Clin Biochem. 2007;44:369–376
  28. Froissart M, Rossert J, Jacquot C, Paillard M, Houillier P. Predictive performance of the Modification of Diet in Renal Disease and Cockcroft-Gault equations for estimating renal function. J Am Soc Nephrol. 2005;16:763–773
  29. Bird NJ, Peters C, Michell AR, Peters AM. Using the slope-only technique and eGFR for checking the reliability of slope-intercept measurement of glomerular filtration rate. Nucl Med Commun. 2008;29:1086–1092
  30. De Sadeleer C, Piepsz A, Ham HR. Post-test quality control for the single blood sample technique in glomerular filtration rate measurement in children. Nucl Med Commun. 2006;27:255–260

PII: S0272-6386(09)00747-1

doi: 10.1053/j.ajkd.2009.03.026

American Journal of Kidney Diseases
Volume 54, Issue 2 , Pages 278-288 , August 2009

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