American Journal of Kidney Diseases
Volume 54, Issue 3 , Pages 554-560, September 2009

Evolving Statistical Methods to Facilitate Evaluation of the Causal Association Between Erythropoiesis-Stimulating Agent Dose and Mortality in Nonexperimental Research: Strengths and Limitations

  • Brian D. Bradbury, MA, DSc

      Affiliations

    • Department of Biostatistics and Epidemiology, Amgen Inc, Thousand Oaks, CA
    • Corresponding Author InformationAddress correspondence to Brian D. Bradbury, MA, DSc, Department of Biostatistics & Epidemiology, Amgen Inc, One Amgen Center Dr, MS: 24-2-A, Thousands Oaks, CA 91320
    • ,
  • M. Alan Brookhart, PhD

      Affiliations

    • Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA
    • ,
  • Wolfgang C. Winkelmayer, MD, ScD, MPH

      Affiliations

    • Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA
    • Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA
    • ,
  • Cathy W. Critchlow, PhD

      Affiliations

    • Department of Biostatistics and Epidemiology, Amgen Inc, Thousand Oaks, CA
    • ,
  • Ryan D. Kilpatrick, PhD

      Affiliations

    • Department of Biostatistics and Epidemiology, Amgen Inc, Thousand Oaks, CA
    • ,
  • Marshall M. Joffe, MD, PhD, MPH

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
    • ,
  • Harold I. Feldman, MD, MSCE

      Affiliations

    • Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
    • Department of Medicine, University of Pennsylvania, Philadelphia, PA
    • ,
  • John F. Acquavella, PhD

      Affiliations

    • Department of Biostatistics and Epidemiology, Amgen Inc, Thousand Oaks, CA
    • ,
  • Ouhong Wang, PhD

      Affiliations

    • Department of Biostatistics and Epidemiology, Amgen Inc, Thousand Oaks, CA
    • ,
  • Kenneth J. Rothman, DrPH

      Affiliations

    • Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA
    • RTI Health Solutions, Research Triangle Park, NC

Received 19 December 2008; accepted 6 May 2009. published online 10 July 2009.

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 Originally published online as doi: 10.1053/j.ajkd.2009.05.010 on July 10, 2009.

 Because an author of this manuscript is an editor for AJKD, the peer-review and decision-making processes were handled entirely by an Associate Editor (Adeera Levin, MD, University of British Columbia) who served as Acting Editor-in-Chief. Details of the journal's procedures for potential editor conflicts are given in the Editorial Policies section of the AJKD website.

PII: S0272-6386(09)00833-6

doi:10.1053/j.ajkd.2009.05.010

American Journal of Kidney Diseases
Volume 54, Issue 3 , Pages 554-560, September 2009

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