American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 386-390 , February 2010

An Uncommon Cause of Membranous Glomerulonephritis

  • Anjali A. Satoskar, MD

      Affiliations

    • Department of Pathology, Ohio State University Medical Center, Columbus, OH
    • Corresponding Author InformationAddress correspondence to Anjali A. Satoskar, MD, Clinical Division of Renal and Transplantation Pathology, Department of Pathology, Ohio State University Medical Center, M018 Starling Loving, 320 W 10th Ave, Columbus, OH 43210
    • ,
  • Paul Kovach, MD

      Affiliations

    • Mount Carmel East Hospital, Columbus, OH
    • ,
  • Kevin O'Reilly, MD

      Affiliations

    • Mount Carmel East Hospital, Columbus, OH
    • ,
  • Tibor Nadasdy, MD, PhD

      Affiliations

    • Department of Pathology, Ohio State University Medical Center, Columbus, OH

Received 2 February 2009 ,Accepted 9 June 2009.

  • Image Result

    Hematoxylin and eosin–stained paraffin-embedded section. The glomerulus looks unremarkable (original magnification ×400).

    Hematoxylin and eosin–stained paraffin-embedded section. The glomerulus looks unremarkable (original magnification ×400).

  • Image Result

    Staining pattern for immunoglobulin G (IgG) subtypes. (A) Direct immunofluorescence shows moderate granular staining for IgG1 along the glomerular capillary wall, (B) absent staining for IgG2, (C) mil

    Staining pattern for immunoglobulin G (IgG) subtypes. (A) Direct immunofluorescence shows moderate granular staining for IgG1 along the glomerular capillary wall, (B) absent staining for IgG2, (C) mild granular staining for IgG3 along the glomerular capillary wall, and (D) absent staining for IgG4 (frozen section; original magnification ×400).

  • Image Result
    Electron micrograph shows scattered subepithelial electron-dense immune-type deposits, irregularly distributed (arrows) (uranyl acetate lead citrate staining; original magnification ×12,000).

    Electron micrograph shows scattered subepithelial electron-dense immune-type deposits, irregularly distributed (arrows) (uranyl acetate lead citrate staining; original magnification ×12,000).

  • Image Result
    Electron micrograph shows endothelial tubuloreticular inclusion (arrow) (uranyl acetate lead citrate staining; original magnification ×30,000).

    Electron micrograph shows endothelial tubuloreticular inclusion (arrow) (uranyl acetate lead citrate staining; original magnification ×30,000).

 Originally published online as doi:10.1053/j.ajkd.2009.06.015 on July 31, 2009.

PII: S0272-6386(09)00878-6

doi: 10.1053/j.ajkd.2009.06.015

American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 386-390 , February 2010

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