American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 386-390 , February 2010

An Uncommon Cause of Membranous Glomerulonephritis

  • Anjali A. Satoskar, MD

      Affiliations

    • Department of Pathology, Ohio State University Medical Center, Columbus, OH
    • Corresponding Author InformationAddress correspondence to Anjali A. Satoskar, MD, Clinical Division of Renal and Transplantation Pathology, Department of Pathology, Ohio State University Medical Center, M018 Starling Loving, 320 W 10th Ave, Columbus, OH 43210
    • ,
  • Paul Kovach, MD

      Affiliations

    • Mount Carmel East Hospital, Columbus, OH
    • ,
  • Kevin O'Reilly, MD

      Affiliations

    • Mount Carmel East Hospital, Columbus, OH
    • ,
  • Tibor Nadasdy, MD, PhD

      Affiliations

    • Department of Pathology, Ohio State University Medical Center, Columbus, OH

Received 2 February 2009 ,Accepted 9 June 2009.

References 

  1. Ohtani H, Wakui H, Komatsuda A, et al. Distribution of glomerular IgG subclass deposits in malignancy-associated membranous nephropathy. Nephrol Dial Transplant. 2004;19:574–579
  2. Kuroki A, Shibata T, Honda H, et al. Glomerular and serum IgG subclasses in diffuse proliferative lupus nephritis, membranous lupus nephritis, and idiopathic membranous nephropathy. Intern Med. 2002;41:936–942
  3. Hunt W, Al-Ghraoui F, Cohen RJ. Secondary syphilis and nephrotic syndrome. J Am Soc Nephrol. 1993;3:1351–1355
  4. Hruby Z, Kuüniar J, Rabczyński J, et al. The variety of clinical and histopathological presentations of glomerulonephritis associated with latent syphilis. Int Urol Nephrol. 1992;24:541–547
  5. Sanchez-Bayle M, Ecija JL, Estepa R, et al. Incidence of glomerulonephritis in congenital syphilis. Clin Nephrol. 1983;20:27–31
  6. Koenig M, Duband S, Thibaudin D, et al. [Rash and nephrotic syndrome: Consider syphilis]. Presse Med. 2005;34:657
  7. Gottlieb SL, Pope V, Sternberg MR, et al. Prevalence of syphilis seroreactivity in the United States: Data from the National Health and Nutrition Examination Surveys (NHANES) 2001-2004. Sex Transm Dis. 2008;35:507–511
  8. Hahn RA, Magder LS, Aral SO, et al. Race and the prevalence of syphilis seroreactivity in the United States population: A national sero-epidemiologic study. Am J Public Health. 1989;79:467–470
  9. Nakashima AK, Rolfs RT, Flock ML, et al. Epidemiology of syphilis in the United States, 1941-1993. Sex Transm Dis. 1996;23:16–23
  10. Soehardy Z, Hayati SN, Rozita M, et al. Subclinical acquired syphilis masquerading as membranous glomerulonephritis. Med J Malaysia. 2006;61:484–486
  11. Wiggelinkhuizen J, Sinclair-Smith C. Membranous glomerulonephropathy in childhood. S Afr Med J. 1987;72:184–187
  12. Cahen R, Francois B, Trolliet P, et al. Aetiology of membranous glomerulonephritis: A prospective study of 82 adult patients. Nephrol Dial Transplant. 1989;4:172–180
  13. Gamble CN, Reardan JB. Immunopathogenesis of syphilitic glomerulonephritis (Elution of antitreponemal antibody from glomerular immune-complex deposits). N Engl J Med. 1975;292:449–454
  14. Losito A, Bucciarelli E, Massi-Benedetti F, et al. Membranous glomerulonephritis in congenital syphilis. Clin Nephrol. 1979;12:32–37
  15. O'Reagan S, Fong JS, de Chadarévian JP, et al. Treponemal antigens in congenital and acquired syphilis nephritis: Demonstration by immunofluorescence studies. Ann Intern Med. 1976;85:325–327
  16. Inam N, Izhar A, Gonzales Y, et al. Membranous glomerulonephritis secondary to syphilis. Am J Kidney Dis. 2009;53:B43;(abstr 84)
  17. Ponticelli C. Prognosis and treatment of membranous glomerulopathy (Nephrology Forum). Kidney Int. 1986;29:927–940
  18. Poitevin M, Ly M, Daubras M, Ichou F. In vivo study of the sensitivity of Treponema pallidum to ofloxacin. Pathol Biol (Paris). 1988;36:482–487
  19. Une T, Nakajima R, Otani T, Katami K, Osada Y, Otani M. Lack of effectiveness of ofloxacin against experimental syphilis in rabbits. Arzneimittelforschung. 1987;37:1048–1051
  20. Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep. 2006;55(RR-11):1–94
  21. Walker PD, Deeves EC, Sahba G, Wallin JD, O'Neill WM. Rapidly progressive glomerulonephritis in a patient with syphilis (Identification of antitreponemal antibody and treponemal antigen in renal tissue). Am J Med. 1984;76:1106–1112
  22. Mahmoodi BK, ten Kate MK, Waanders F, et al. High absolute risks and predictors of venous and arterial thromboembolic events in patients with nephrotic syndrome: Results from a large retrospective cohort study. Circulation. 2008;117:224–230
  23. Sène Damien, Piette Jean-Charles, Cacoub Patrice. Antiphospholipid antibodies, antiphospholipid syndrome and infections. Autoimmun Rev. 2008;7:272–277

 Originally published online as doi:10.1053/j.ajkd.2009.06.015 on July 31, 2009.

PII: S0272-6386(09)00878-6

doi: 10.1053/j.ajkd.2009.06.015

American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 386-390 , February 2010

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