American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 348-351 , February 2010

Embolic Complications From Central Venous Hemodialysis Catheters Used With Hypertonic Citrate Locking Solution

  • Michelle Kay Willicombe, MRCP

      Affiliations

    • University College London Center for Nephrology, Royal Free Hospital, University College Medical School, London, UK
    • ,
  • Katherine Vernon, MRCP

      Affiliations

    • University College London Center for Nephrology, Royal Free Hospital, University College Medical School, London, UK
    • ,
  • Andrew Davenport, MD

      Affiliations

    • University College London Center for Nephrology, Royal Free Campus, University College Medical School, London, UK
    • Corresponding Author InformationAddress correspondence to Andrew Davenport, MD, UCL Center for Nephrology, Royal Free Campus, University College Medical School London, Rowland Hill St, London NW3 2PF, UK

Received 17 April 2009 ,Accepted 29 June 2009.

References 

  1. Davenport A. Central venous catheters for haemodialysis: how to overcome the problems. Hemodial Int. 2000;4:78–82
  2. Kingdon EJ, Holt SG, Davar J, et al. Atrial thrombus and central venous dialysis catheters. Am J Kidney Dis. 2001;38:631–639
  3. Hassan A, Khalifa M, Al-Akraa M, Lord R, Davenport A. Six cases of retained central venous haemodialysis access catheters. Nephrol Dial Transplant. 2006;21:2005–2008
  4. Moran JE, Ash SR. Clinical Practice Committee (Locking solutions for hemodialysis catheters; heparin and citrate—a position paper by ASDIN). Semin Dial. 2008;21:490–492
  5. Davenport A. Heparin induced thrombocytopenia during renal replacement therapy. Hemodial Int. 2004;8:295–303
  6. Gittins NS, Hunter-Blair YL, Matthews JN, Coulthard MG. Comparison of alteplase and heparin in maintaining the patency of paediatric central venous haemodialysis lines: a randomised controlled trial. Arch Dis Child. 2007;92:499–501
  7. Ash SR. Advances in tunnelled central venous catheters for dialysis: design and performance. Semin Dial. 2008;21:504–515
  8. Coulthard MG, Skinner R. Should paediatric central lines be aspirated before use. Arch Dis Child. 2007;92:517–518
  9. Twardowski ZJ, Moore HL. Side holes at the tip of chronic hemodialysis catheters are harmful. J Vasc Access. 2001;2:8–16
  10. Beathard G. Catheter thrombus. Semin Dial. 2001;14:441–445
  11. Beathard GA, Urbanes A. Infection associated with tunnelled haemodialysis catheters. Semin Dial. 2008;21:528–538
  12. Weijmer MC, van den Dorpel MA, van der Ven PJ, et al. CITRATE Study Group Randomised clinical trial comparison of trisodium citrate 30% and heparin as catheter locking solution in haemodialysis patients. J Am Soc Nephrol. 2005;16:2769–2873
  13. Winnett G, Nolan J, Miller M, Ashman N. Trisodium citrate 46.7% selectively and safely reduces staphylococcal catheter-related bacteraemia. Nephrol Dial Transplant. 2008;23:3592–3598
  14. Lok CE, Appleton D, Bhola C, Khoo B, Richardson RMA. Trisodium citrate 4%—an alternative to heparin capping of hemodialysis catheters. Nephrol Dial Transplant. 2007;22:477–483
  15. Steczko J, Ash SR, Nivens DE, Brewer L, Winger RK. Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens). Nephrol Dial Transplant. 2009;24:1937–1945
  16. Polaschegg HD, Sodemann K. Risks related to catheter locking solutions containing concentrated citrate. Nephrol Dial Transplant. 2003;18:2688–2689
  17. Faintuch S, Salazar GMM. Malfunction of dialysis catheters: management of fibrin sheath and related problems. Tech Vasc Intervent Radiol. 2008;11:195–200
  18. Alomari AI, Falk A. The natural history of tunnelled haemodialysis catheters: removed or exchanged (A single institution experience). J Vasc Intervent Radiol. 2007;18:227–235

 Originally published online as doi:10.1053/j.ajkd.2009.06.037 on October 5, 2009.

PII: S0272-6386(09)00983-4

doi: 10.1053/j.ajkd.2009.06.037

American Journal of Kidney Diseases
Volume 55, Issue 2 , Pages 348-351 , February 2010

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