American Journal of Kidney Diseases
Volume 54, Issue 6 , Pages 1171-1184 , December 2009

Home Hemodialysis, Daily Hemodialysis, and Nocturnal Hemodialysis: Core Curriculum 2009

  • Jeffrey Perl, MD, FRCP(C)
    • ,
  • Christopher T. Chan, MD, FRCP(C)

      Affiliations

    • Corresponding Author InformationAddress correspondence to Christopher T. Chan, MD, FRCP(C), Toronto General Hospital, 200 Elizabeth St-8N-842, Toronto, Ontario, Canada, M5G 2C4

References 

  1. Agar JW, Macgregor MS, Blagg CR. Chronic maintenance hemodialysis: making sense of the terminology. Hemodial Int. 2007;11:252–262
  2. Pereira BJG, Sayegh MH, Blake PG. Chronic kidney disease, dialysis, and transplantation. In:  Pereira BJG,  Sayegh MH,  Blake PG editor. A Companion to Brenner and Rector's The Kidney. Philadelphia, PA: Saunders; 2005;p. 472–480
  3. Scribner BH, Buri R, Caner JE, Hegstrom R, Burnell JM. The treatment of chronic uremia by means of intermittent hemodialysis: a preliminary report. Trans Am Soc Artif Intern Organs. 1960;6:114–122
  4. Shaldon S. Independence in maintenance haemodialysis. Lancet. 1968;1:520
  5. Baillod RCC, Shaldon S. Over-night unattended haemodialysis in the home. Proc EDTA. 1965;2:99–109
  6. Depalma JR, Pecker EA, Maxwell MH. A new automatic coil dialyzer system for ‘daily' dialysis. Hemodial Int. 2004;8:19–23
  7. DePalma JR, Pecker EA, Maxwell MH. A new automatic coil dialyzer system for daily dialysis. Proc Eur Dial Transplant Assoc. 1967;6:26–34
  8. Charra B, Calemard E, Ruffet M, et al. Survival as an index of adequacy of dialysis. Kidney Int. 1992;41:1286–1291
  9. Laurent G, Charra B. The results of an 8 h thrice weekly haemodialysis schedule. Nephrol Dial Transplant. 1998;13(suppl 6):S125–S131
  10. Buoncristiani U, Quintaliani G, Cozzari M, Giombini L, Ragaiolo M. Daily dialysis: long-term clinical metabolic results. Kidney Int Suppl. 1988;24:S137–S140
  11. Buoncristiani U. Fifteen years of clinical experience with daily haemodialysis. Nephrol Dial Transplant. 1998;13(suppl 6):S148–S151
  12. Ting GO, Kjellstrand C, Freitas T, Carrie BJ, Zarghamee S. Long-term study of high-comorbidity ESRD patients converted from conventional to short daily hemodialysis. Am J Kidney Dis. 2003;42:1020–1035
  13. Uldall R, Ouwendyk M, Francoeur R, et al. Slow nocturnal home hemodialysis at the Wellesley Hospital. Adv Ren Replace Ther. 1996;3:133–136
  14. Uldall R, DeBruyne M, Besley M, McMillan J, Simons M, Francoeur R. A new vascular access catheter for hemodialysis. Am J Kidney Dis. 1993;21:270–277
  15. Lockridge RS. Daily dialysis and long-term outcomes—the Lynchburg Nephrology NHHD experience. Nephrol News Issues. 1999;13:16–23
  16. Culleton BF, Walsh M, Klarenbach SW, et al. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial. JAMA. 2007;298:1291–1299
  17. Vonesh EF, Snyder JJ, Foley RN, Collins AJ. Mortality studies comparing peritoneal dialysis and hemodialysis: what do they tell us?. Kidney Int Suppl. 2006;103:S3–S11
  18. Gotch FA. The current place of urea kinetic modelling with respect to different dialysis modalities. Nephrol Dial Transplant. 1998;13(suppl 6):S10–S14
  19. Depner TA. Daily hemodialysis efficiency: an analysis of solute kinetics. Adv Ren Replace Ther. 2001;8:227–235
  20. Casino FG, Lopez T. The equivalent renal urea clearance: a new parameter to assess dialysis dose. Nephrol Dial Transplant. 1996;11:1574–1581
  21. National Kidney Foundation. Guideline I. NKF-K/DOQI Clinical Practice Guidelines for Hemodialysis Adequacy: update 2000. In: K/DOQI Clinical Practice Guidelines: update 2000. Am J Kidney Dis. 2001;37(suppl 1):S7–S64
  22. National Kidney Foundation. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Hemodialysis Adequacy, update 2006 (In: KDOQI Clinical Practice Guidelines for Hemodialysis Adequacy, update 2006). Am J Kidney Dis. 2006;48(suppl 1):S2–S90
  23. Suri R, Depner TA, Blake PG, Heidenheim AP, Lindsay RM. Adequacy of quotidian hemodialysis. Am J Kidney Dis. 2003;42:42–48
  24. Clark WR, Leypoldt JK, Henderson LW, Mueller BA, Scott MK, Vonesh EF. Quantifying the effect of changes in the hemodialysis prescription on effective solute removal with a mathematical model. J Am Soc Nephrol. 1999;10:601–609
  25. Goldfarb-Rumyantzev AS, Cheung AK, Leypoldt JK. Computer simulation of small-solute and middle-molecule removal during short daily and long thrice-weekly hemodialysis. Am J Kidney Dis. 2002;40:1211–1218
  26. Pierratos A. Effect of therapy time and frequency on effective solute removal. Semin Dial. 2001;14:284–288
  27. Raj DS, Ouwendyk M, Francoeur R, Pierratos A. Beta(2)-microglobulin kinetics in nocturnal haemodialysis. Nephrol Dial Transplant. 2000;15:58–64
  28. Eloot S, Van Biesen W, Dhondt A, et al. Impact of hemodialysis duration on the removal of uremic retention solutes. Kidney Int. 2008;73:765–770
  29. Fagugli RM, Vanholder R, De Smet R, et al. Advanced glycation end products: specific fluorescence changes of pentosidine-like compounds during short daily hemodialysis. Int J Artif Organs. 2001;24:256–262
  30. Blagg CR. A brief history of home hemodialysis. Adv Ren Replace Ther. 1996;3:99–105
  31. US Renal Data System (USRDS 2008 Annual Data Report). In: Bethesda MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2008;p. 98
  32. MacGregor MS, Agar JW, Blagg CR. Home haemodialysis—international trends and variation. Nephrol Dial Transplant. 2006;21:1934–1945
  33. Chan CT, Jain V, Picton P, Pierratos A, Floras JS. Nocturnal hemodialysis increases arterial baroreflex sensitivity and compliance and normalizes blood pressure of hypertensive patients with end-stage renal disease. Kidney Int. 2005;68:338–344
  34. McCormick BB, Chan CT. Improved blood pressure control with nocturnal hemodialysis: review of clinical observations and physiologic mechanisms. Curr Hypertens Rep. 2004;6:140–144
  35. Chan C, Floras JS, Miller JA, Pierratos A. Improvement in ejection fraction by nocturnal haemodialysis in end-stage renal failure patients with coexisting heart failure. Nephrol Dial Transplant. 2002;17:1518–1521
  36. Pauly RP, Sood MM, Chan CT. Management of refractory ascites using nocturnal home hemodialysis. Semin Dial. 2008;21:367–370
  37. Kim SJ, Goldstein M, Szabo T, Pierratos A. Resolution of massive uremic tumoral calcinosis with daily nocturnal home hemodialysis. Am J Kidney Dis. 2003;41:E12
  38. Mucsi I, Hercz G, Uldall R, Ouwendyk M, Francoeur R, Pierratos A. Control of serum phosphate without any phosphate binders in patients treated with nocturnal hemodialysis. Kidney Int. 1998;53:1399–1404
  39. Toussaint N, Boddington J, Simmonds R, Waldron C, Somerville C, Agar J. Calcium phosphate metabolism and bone mineral density with nocturnal hemodialysis. Hemodial Int. 2006;10:280–286
  40. Hanly PJ, Pierratos A. Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med. 2001;344:102–107
  41. Wong JH, Pierratos A, Oreopoulos DG, Mohammad R, Benjamin-Wong F, Chan CT. The use of nocturnal home hemodialysis as salvage therapy for patients experiencing peritoneal dialysis failure. Perit Dial Int. 2007;27:669–674
  42. Faratro R, D'Gama C, Chan C. The use of alternative anti-coagulation strategies for a nocturnal home hemodialysis patient with heparin-induced thrombocytopenia. CANNT J. 2008;18:32–35
  43. Cafazzo JA, Leonard K, Easty AC, Rossos PG, Chan CT. Patient-perceived barriers to the adoption of nocturnal home hemodialysis. Clin J Am Soc Nephrol. 2009;4:784–789
  44. McLaughlin K, Manns B, Mortis G, Hons R, Taub K. Why patients with ESRD do not select self-care dialysis as a treatment option. Am J Kidney Dis. 2003;41:380–385
  45. Mehrabian S, Morgan D, Schlaeper C, Kortas C, Lindsay RM. Equipment and water treatment considerations for the provision of quotidian home hemodialysis. Am J Kidney Dis. 2003;42:66–70
  46. Piccoli GB, Jeantet A, Gai M, et al. Home dialysis, garbage, and privacy: nothing is trivial in home hemodialysis [letter]. Kidney Int. 2005;67:1190
  47. Piccoli GB, Bermond F, Mezza E, et al. Vascular access survival and morbidity on daily dialysis: a comparative analysis of home and limited care haemodialysis. Nephrol Dial Transplant. 2004;19:2084–2094
  48. Pierratos A, Ouwendyk M, Francoeur R, et al. Nocturnal hemodialysis: three-year experience. J Am Soc Nephrol. 1998;9:859–868
  49. Pierratos A. Nocturnal home haemodialysis: an update on a 5-year experience. Nephrol Dial Transplant. 1999;14:2835–2840
  50. Twardowski Z, Kubara H. Different sites versus constant sites of needle insertion into arteriovenous fistulas for treatment by repeated dialysis. Dial Transplant. 1979;8:978–980
  51. Verhallen AM, Kooistra MP, van Jaarsveld BC. Cannulating in haemodialysis: rope-ladder or buttonhole technique?. Nephrol Dial Transplant. 2007;22:2601–2604
  52. Ahlmen J, Gydell KH, Hadimeri H, Hernandez I, Rogland B, Strombom U. A new safety device for hemodialysis. Hemodial Int. 2008;12:264–267
  53. Suri RS, Nesrallah GE, Mainra R, et al. Daily hemodialysis: a systematic review. Clin J Am Soc Nephrol. 2006;1:33–42
  54. Lindsay RM. The London, Ontario, Daily/Nocturnal Hemodialysis Study. Semin Dial. 2004;17:85–91
  55. Perl J, Lok CE, Chan CT. Central venous catheter outcomes in nocturnal hemodialysis. Kidney Int. 2006;70:1348–1354
  56. Hoy C. Remote monitoring in nocturnal home hemodialysis 2003. Hemodial Int. 2004;8:144–150
  57. Heidenheim AP, Leitch R, Kortas C, Lindsay RM. Patient monitoring in the London Daily/Nocturnal Hemodialysis Study. Am J Kidney Dis. 2003;42:61–65
  58. Ledebo I, Fredin R. The Gambro system for home daily dialysis. Semin Dial. 2004;17:162–163
  59. Schlaeper C, Diaz-Buxo JA. The Fresenius Medical Care home hemodialysis system. Semin Dial. 2004;17:159–161
  60. Kelly TD. Baxter Aurora dialysis system. Semin Dial. 2004;17:154–155
  61. Trewin E. Bellco Formula Domus Home Care System. Semin Dial. 2004;17:156–158
  62. Kjellstrand CM, Blagg CR, Bower J, Twardowski ZJ. The Aksys personal hemodialysis system. Semin Dial. 2004;17:151–153
  63. Clark WR, Turk JE. The NxStage System One. Semin Dial. 2004;17:167–170
  64. Ash SR. The Allient dialysis system. Semin Dial. 2004;17:164–166
  65. Fagugli RM, Reboldi G, Quintaliani G, et al. Short daily hemodialysis: blood pressure control and left ventricular mass reduction in hypertensive hemodialysis patients. Am J Kidney Dis. 2001;38:371–376
  66. Chan CT, Floras JS, Miller JA, Richardson RM, Pierratos A. Regression of left ventricular hypertrophy after conversion to nocturnal hemodialysis. Kidney Int. 2002;61:2235–2239
  67. Nesrallah G, Suri R, Moist L, Kortas C, Lindsay RM. Volume control and blood pressure management in patients undergoing quotidian hemodialysis. Am J Kidney Dis. 2003;42:13–17
  68. Fagugli RM, Pasini P, Pasticci F, Ciao G, Cicconi B, Buoncristiani U. Effects of short daily hemodialysis and extended standard hemodialysis on blood pressure and cardiac hypertrophy: a comparative study. J Nephrol. 2006;19:77–83
  69. Chan CT, Harvey PJ, Picton P, Pierratos A, Miller JA, Floras JS. Short-term blood pressure, noradrenergic, and vascular effects of nocturnal home hemodialysis. Hypertension. 2003;42:925–931
  70. Walsh M, Culleton B, Tonelli M, Manns B. A systematic review of the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Kidney Int. 2005;67:1500–1508
  71. Chan CT, Li SH, Verma S. Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease. Am J Physiol Renal Physiol. 2005;289:F679–F684
  72. Yuen D, Pierratos A, Richardson RM, Chan CT. The natural history of coronary calcification progression in a cohort of nocturnal haemodialysis patients. Nephrol Dial Transplant. 2006;21:1407–1412
  73. Chan CT, Hanly P, Gabor J, Picton P, Pierratos A, Floras JS. Impact of nocturnal hemodialysis on the variability of heart rate and duration of hypoxemia during sleep. Kidney Int. 2004;65:661–665
  74. Zilch O, Vos PF, Oey PL, et al. Sympathetic hyperactivity in haemodialysis patients is reduced by short daily haemodialysis. J Hypertens. 2007;25:1285–1289
  75. Woods JD, Port FK, Orzol S, et al. Clinical and biochemical correlates of starting “daily” hemodialysis. Kidney Int. 1999;55:2467–2476
  76. Schwartz DI, Pierratos A, Richardson RM, Fenton SS, Chan CT. Impact of nocturnal home hemodialysis on anemia management in patients with end-stage renal disease. Clin Nephrol. 2005;63:202–208
  77. Chan CT, Liu PP, Arab S, Jamal N, Messner HA. Nocturnal hemodialysis improves erythropoietin responsiveness and growth of hematopoietic stem cells. J Am Soc Nephrol. 2009;20:665–671
  78. Yuen D, Richardson RM, Chan CT. Improvements in phosphate control with short daily in-center hemodialysis. Clin Nephrol. 2005;64:364–370
  79. Kooistra MP, Vos J, Koomans HA, Vos PF. Daily home haemodialysis in The Netherlands: effects on metabolic control, haemodynamics, and quality of life. Nephrol Dial Transplant. 1998;13:2853–2860
  80. Barua M, Hladunewich M, Keunen J, et al. Successful pregnancies on nocturnal home hemodialysis. Clin J Am Soc Nephrol. 2008;3:392–396
  81. Ing TS, Yu AW, Agrawal B, et al. Increasing plasma phosphorus values by enriching with phosphorus the “acid concentrate” of a bicarbonate-buffered dialysate delivery system. Int J Artif Organs. 1992;15:701–703
  82. Al-Hejaili F, Kortas C, Leitch R, et al. Nocturnal but not short hours quotidian hemodialysis requires an elevated dialysate calcium concentration. J Am Soc Nephrol. 2003;14:2322–2328
  83. Nessim SJ, Jassal SV, Fung SV, Chan CT. Conversion from conventional to nocturnal hemodialysis improves vitamin D levels. Kidney Int. 2007;71:1172–1176
  84. McPhatter LL, Lockridge RS, Albert J, et al. Nightly home hemodialysis: improvement in nutrition and quality of life. Adv Ren Replace Ther. 1999;6:358–365
  85. Spanner E, Suri R, Heidenheim AP, Lindsay RM. The impact of quotidian hemodialysis on nutrition. Am J Kidney Dis. 2003;42:30–35
  86. Galland R, Traeger J, Arkouche W, Cleaud C, Delawari E, Fouque D. Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients. Kidney Int. 2001;60:1555–1560
  87. Galland R, Traeger J, Arkouche W, Delawari E, Fouque D. Short daily hemodialysis and nutritional status. Am J Kidney Dis. 2001;37(suppl):S95–S98
  88. Raj DS, Ouwendyk M, Francoeur R, Pierratos A. Plasma amino acid profile on nocturnal hemodialysis. Blood Purif. 2000;18:97–102
  89. Chazot C, Vo VC, Blanc C, et al. Stability of nutritional parameters during a 5-year follow-up in patients treated with sequential long-hour hemodialysis. Hemodial Int. 2006;10:389–393
  90. Yuen D, Richardson RM, Fenton SS, McGrath-Chong ME, Chan CT. Quotidian nocturnal hemodialysis improves cytokine profile and enhances erythropoietin responsiveness. ASAIO J. 2005;51:236–241
  91. Perl J, Unruh ML, Chan CT. Sleep disorders in end-stage renal disease: ‘markers of inadequate dialysis'?. Kidney Int. 2006;70:1687–1693
  92. Lavie P, Lavie L. Cardiovascular morbidity and mortality in obstructive sleep apnea. Curr Pharm Des. 2008;14:3466–3473
  93. Hanly PJ, Gabor JY, Chan C, Pierratos A. Daytime sleepiness in patients with CRF: impact of nocturnal hemodialysis. Am J Kidney Dis. 2003;41:403–410
  94. Bagon JA, Vernaeve H, De Muylder X, Lafontaine JJ, Martens J, Van Roost G. Pregnancy and dialysis. Am J Kidney Dis. 1998;31:756–765
  95. Bamberg C, Diekmann F, Haase M, et al. Pregnancy on intensified hemodialysis: fetal surveillance and perinatal outcome. Fetal Diagn Ther. 2007;22:289–293
  96. Okundaye I, Abrinko P, Hou S. Registry of pregnancy in dialysis patients. Am J Kidney Dis. 1998;31:766–773
  97. Jassal SV, Devins GM, Chan CT, Bozanovic R, Rourke S. Improvements in cognition in patients converting from thrice weekly hemodialysis to nocturnal hemodialysis: a longitudinal pilot study. Kidney Int. 2006;70:956–962
  98. Bell CM, Chapman RH, Stone PW, Sandberg EA, Neumann PJ. An off-the-shelf help list: a comprehensive catalog of preference scores from published cost-utility analyses. Med Decis Making. 2001;21:288–294
  99. Mohr PE, Neumann PJ, Franco SJ, Marainen J, Lockridge R, Ting G. The case for daily dialysis: its impact on costs and quality of life. Am J Kidney Dis. 2001;37:777–789
  100. Manns BJ, Walsh MW, Culleton BF, et al. Nocturnal hemodialysis does not improve overall measures of quality of life compared to conventional hemodialysis. Kidney Int. 2009;75:542–549
  101. Fong E, Bargman JM, Chan CT. Cross-sectional comparison of quality of life and illness intrusiveness in patients who are treated with nocturnal home hemodialysis versus peritoneal dialysis. Clin J Am Soc Nephrol. 2007;2:1195–1200
  102. McFarlane PA, Bayoumi AM, Pierratos A, Redelmeier DA. The quality of life and cost utility of home nocturnal and conventional in-center hemodialysis. Kidney Int. 2003;64:1004–1011
  103. Heidenheim AP, Muirhead N, Moist L, Lindsay RM. Patient quality of life on quotidian hemodialysis. Am J Kidney Dis. 2003;42:36–41
  104. McFarlane PA. Reducing hemodialysis costs: conventional and quotidian home hemodialysis in Canada. Semin Dial. 2004;17:118–124
  105. Bergman A, Fenton SS, Richardson RM, Chan CT. Reduction in cardiovascular related hospitalization with nocturnal home hemodialysis. Clin Nephrol. 2008;69:33–39
  106. McFarlane PA, Pierratos A, Redelmeier DA. Cost savings of home nocturnal versus conventional in-center hemodialysis. Kidney Int. 2002;62:2216–2222
  107. Kroeker A, Clark WF, Heidenheim AP, et al. An operating cost comparison between conventional and home quotidian hemodialysis. Am J Kidney Dis. 2003;42:49–55
  108. Pierratos A. Daily nocturnal home hemodialysis. Kidney Int. 2004;65:1975–1986
  109. Charra B, Terrat JC, Vanel T, et al. Long thrice weekly hemodialysis: the Tassin experience. Int J Artif Organs. 2004;27:265–283
  110. Marshall MR, Byrne BG, Kerr PG, McDonald SP. Associations of hemodialysis dose and session length with mortality risk in Australian and New Zealand patients. Kidney Int. 2006;69:1229–1236
  111. Kjellstrand CM, Buoncristiani U, Ting G, et al. Short daily haemodialysis: survival in 415 patients treated for 1006 patient-years. Nephrol Dial Transplant. 2008;23:3283–3289
  112. Woods JD, Port FK, Stannard D, Blagg CR, Held PJ. Comparison of mortality with home hemodialysis and center hemodialysis: a national study. Kidney Int. 1996;49:1464–1470
  113. Pauly RP. Nocturnal home hemodialysis and short daily hemodialysis compared with kidney transplantation: emerging data in a new era. Adv Chronic Kidney Dis. 2009;16:169–172
  114. Nesrallah GE, Suri RS, Carter ST, et al. The International Quotidian Dialysis Registry: annual report 2007. Hemodial Int. 2007;11:271–277
  115. Nesrallah GE, Moist LM, Awaraji C, Lindsay RM. An international registry to compare quotidian dialysis regimens with conventional thrice-weekly hemodialysis: why, how, and potential pitfalls. Semin Dial. 2004;17:131–135
  116. Pauly RP, Boivin JF, Chan CT. Methodological considerations for research in nocturnal home hemodialysis. J Nephrol. 2007;20:381–387
  117. Kliger AS. High-frequency hemodialysis: rationale for randomized clinical trials. Clin J Am Soc Nephrol. 2007;2:390–392
  118. Greene T, Daugirdas JT, Depner TA, Gotch F, Kuhlman M. Solute clearances and fluid removal in the frequent hemodialysis network trials. Am J Kidney Dis. 2009;53:835–844
  119. Eknoyan G, Beck GJ, Cheung AK, et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med. 2002;347:2010–2019

 Originally published online as doi: 10.1053/j.ajkd.2009.06.038 on September 14, 2009.

PII: S0272-6386(09)00984-6

doi: 10.1053/j.ajkd.2009.06.038

American Journal of Kidney Diseases
Volume 54, Issue 6 , Pages 1171-1184 , December 2009

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