American Journal of Kidney Diseases
Volume 54, Issue 6 , Pages 1089-1097 , December 2009

Ascorbic Acid for Anemia Management in Hemodialysis Patients: A Systematic Review and Meta-analysis

  • Vinay Deved, MD

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Penelope Poyah, MD

      Affiliations

    • Department of Medicine, Dalhouise University, Halifax, Nova Scotia, Canada
    • ,
  • Matthew T. James, MD

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Marcello Tonelli, MD, SM

      Affiliations

    • Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    • ,
  • Braden J. Manns, MD, MSc

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Michael Walsh, MD

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Brenda R. Hemmelgarn, MD, PhD

      Affiliations

    • Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    • Corresponding Author InformationAddress correspondence to Brenda R. Hemmelgarn, MD, PhD, Division of Nephrology, Foothills Medical Centre, 1403 29th St NW, Calgary, Alberta, Canada T2N 2T9
    • ,
  • Alberta Kidney Disease Network

Received 23 March 2009 ,Accepted 29 June 2009.

  • Image Result

    Identification of studies. Abbreviation: RCT, randomized controlled trial.

    Identification of studies. Abbreviation: RCT, randomized controlled trial.

  • Image Result

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in hemoglobin concentration (grams per deciliter). Abbreviation: CI, confidence interval.

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in hemoglobin concentration (grams per deciliter). Abbreviation: CI, confidence interval.

  • Image Result

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in recombinant human erythropoietin dose (units per kilogram per week). Abbreviation: CI, confidence interval.

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in recombinant human erythropoietin dose (units per kilogram per week). Abbreviation: CI, confidence interval.

  • Image Result

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in ferritin concentration (micrograms per liter). Abbreviation: CI, confidence interval.

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in ferritin concentration (micrograms per liter). Abbreviation: CI, confidence interval.

  • Image Result

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in transferrin saturation (percentage). Abbreviation: CI, confidence interval.

    Forest plot of studies comparing the effect of ascorbic acid versus control on change in transferrin saturation (percentage). Abbreviation: CI, confidence interval.

 Originally published online as doi:10.1053/j.ajkd.2009.06.040 on September 24, 2009.

PII: S0272-6386(09)00988-3

doi: 10.1053/j.ajkd.2009.06.040

American Journal of Kidney Diseases
Volume 54, Issue 6 , Pages 1089-1097 , December 2009

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