American Journal of Kidney Diseases
Volume 55, Issue 3 , Pages 604-608 , March 2010

Recurrent Pauci-immune Necrotizing Crescentic Glomerulonephritis in a Kidney Transplant Patient

  • Heidi M. Schaefer, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN
    • Corresponding Author InformationAddress correspondence to Heidi M. Schaefer, MD, Division of Nephrology, S-3223 MCN, Vanderbilt University Medical Center, 21st Ave S, Nashville, TN 37232-2372
    • ,
  • Anthony Langone, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN
    • ,
  • J. Harold Helderman, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN
    • ,
  • Agnes B. Fogo, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN
    • Department of Pathology, Vanderbilt University Medical Center, Nashville, TN

Received 24 April 2009 ,Accepted 27 July 2009.

References 

  1. Weidemann S, Andrassy K, Ritz E. ANCA in haemodialysis patients. Nephrol Dial Transplant. 1993;8:839–845
  2. Allen A, Pusey C, Gaskin G. Outcome of renal replacement therapy in antineutrophil cytoplasmic antibody-associated systemic vasculitis. J Am Soc Nephrol. 1998;9:1258–1263
  3. Nachman PH, Segelmark M, Westman K, et al. Recurrent ANCA-associated small vessel vasculitis after transplantation: a pooled analysis. Kidney Int. 1999;56:1544–1550
  4. Jennette JC. Rapidly progressive crescentic glomerulonephritis. Kidney Int. 2003;63:1164–1177
  5. Jennette JC, Falk RJ, Andrassy K, et al. Nomenclature of systemic vasculitides (Proposal of an international consensus conference). Arthritis Rheum. 1994;37:187–192
  6. Haubitz M, Koch KM, Brunkhorst R. Survival and vasculitis activity in patients with end-stage renal disease due to Wegener's granulomatosis. Nephrol Dial Transplant. 1998;13:1713–1718
  7. Rostaing L, Modesto A, Oksman F, Cisterne JM, Le Mao G, Durand D. Outcome of patients with antineutrophil cytoplasmic autoantibody-associated vasculitis following cadaveric kidney transplantation. Am J Kidney Dis. 1997;29:96–102
  8. Schmitt WH, Haubitz M, Mistry N, Brunkhorst R, Erbsloh-Moller B, Gross WL. Renal transplantation in Wegener's granulomatosis [letter]. Lancet. 1993;342:860
  9. Tervaert JW, Huitema MG, Hene RJ, et al. Prevention of relapses in Wegener's granulomatosis by treatment based on antineutrophil cytoplasmic antibody titre. Lancet. 1990;336:709–711
  10. Boomsma MM, Stegeman CA, van der Leij MJ, et al. Prediction of relapses in Wegener's granulomatosis by measurement of antineutrophil cytoplasmic antibody levels: a prospective study. Arthritis Rheum. 2000;43:2025–2033
  11. Briganti EM, Russ GR, McNeil JJ, Atkins RC, Chadban SJ. Risk of renal allograft loss from recurrent glomerulonephritis. N Engl J Med. 2002;347:103–109
  12. Haubitz M, Kliem V, Koch KM, et al. Renal transplantation for patients with autoimmune diseases: single-center experience with 42 patients. Transplantation. 1997;63:1251–1257
  13. Elmedhem A, Adu D, Savage CO. Relapse rate and outcome of ANCA-associated small vessel vasculitis after transplantation. Nephrol Dial Transplant. 2003;18:1001–1004
  14. Turney JH, Adu D, Michael J, McMaster P. Recurrent crescentic glomerulonephritis in renal transplant recipient treated with cyclosporin [letter]. Lancet. 1986;1:1104

 Originally published online as doi:10.1053/j.ajkd.2009.07.019 on September 27, 2009.

PII: S0272-6386(09)01074-9

doi: 10.1053/j.ajkd.2009.07.019

American Journal of Kidney Diseases
Volume 55, Issue 3 , Pages 604-608 , March 2010

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