American Journal of Kidney Diseases
Volume 55, Issue 3 , Pages 590-598 , March 2010

Hypertension in the Developing World: Challenges and Opportunities

  • Bharati V. Mittal, MD
  • ,
  • Ajay K. Singh, MBBS, MBA, FRCP

      Affiliations

    • Corresponding Author InformationAddress correspondence to Ajay K. Singh, MBBS, MBA, FRCP, Renal Division, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115

References 

  1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365(9455):217–223
  2. Gupta R, Sharma AK. Prevalence of hypertension and subtypes in an Indian rural population: clinical and electrocardiographic correlates. J Hum Hypertens. 1994;8(11):823–829
  3. Gupta R, Guptha S, Gupta VP, Prakash H. Prevalence and determinants of hypertension in the urban population of Jaipur in western India. J Hypertens. 1995;13(10):1193–1200
  4. Malhotra P, Kumari S, Kumar R, Jain S, Sharma BK. Prevalence and determinants of hypertension in an un-industrialised rural population of north India. J Hum Hypertens. 1999;13(7):467–472
  5. Das SK, Sanyal K, Basu A. Study of urban community survey in India: growing trend of high prevalence of hypertension in a developing country. Int J Med Sci. 2005;2(2):70–78
  6. Wang Z, Wu Y, Zhao L, et al. Trends in prevalence, awareness, treatment and control of hypertension in the middle-aged population of China, 1992-1998. Hypertens Res. 2004;27(10):703–709
  7. Ahmad K, Jafar TH. Prevalence and determinants of blood pressure screening in Pakistan. J Hypertens. 2005;23(11):1979–1984
  8. Ibrahim MM, Appel LJ, Rizk HH, Helmy S, Mosley J, Ashour Z, et al. Hypertension prevalence, awareness, treatment, and control in Egypt (Results from the Egyptian National Hypertension Project (NHP). NHP Investigative Team). Hypertension. 1995;26:886–890
  9. Mbanya JC, Minkoulou EM, Salah JN, Balkau B. The prevalence of hypertension in rural and urban Cameroon. Int J Epidemiol. 1998;27(2):181–185
  10. Agyemang C. Rural and urban differences in blood pressure and hypertension in Ghana, West Africa. Public Health. 2006;120(6):525–533
  11. Schargrodsky H, Hernandez-Hernandez R, Champagne BM, et al. CARMELA: assessment of cardiovascular risk in seven Latin American cities. Am J Med. 2008;121(1):58–65
  12. Collins AJ, Kasiske B, Herzog C, et al. Excerpts from the United States Renal Data System 2006 Annual Data Report. Am J Kidney Dis. 2007;49(1 suppl 1):A6–A7S1-296
  13. Burt VL, Whelton P, Roccella EJ, et al. Prevalence of hypertension in the US adult population (Results from the Third National Health and Nutrition Examination Survey, 1988-1991). Hypertension. 1995;25(3):305–313
  14. Pobee JO, Larbi EB, Belcher DW, Wurapa FK, Dodu SR. Blood pressure distribution in a rural Ghanaian population. Trans R Soc Trop Med Hyg. 1977;71(1):66–72
  15. Oviasu VO. Arterial blood pressures and hypertension in a rural Nigerian community. Afr J Med Med Sci. 1978;7(3):137–143
  16. Mokhobo KP. Arterial hypertension in rural societies. East Afr Med J. 1976;53(8):440–444
  17. Seedat YK, Seedat MA, Hackland DB. Prevalence of hypertension in the urban and rural Zulu. J Epidemiol Community Health. 1982;36(4):256–261
  18. Addo J, Smeeth L, Leon DA. Hypertension in sub-Saharan Africa: a systematic review. Hypertension. 2007;50(6):1012–1018
  19. Cappuccio FP, Micah FB, Emmett L, et al. Prevalence, detection, management, and control of hypertension in Ashanti, West Africa. Hypertension. 2004;43(5):1017–1022
  20. Steyn K, Gaziano TA, Bradshaw D, Laubscher R, Fourie J South African Demographic and Health Coordinating Team. Hypertension in South African adults: results from the demographic and health survey, 1998. J Hypertens. 2001;19(10):1717–1725
  21. Dash SC, Sundaram KR, Swain PK. Blood pressure profile, urinary sodium and body weight in the ‘oraon’ rural and urban tribal community. J Assoc Physicians India. 1994;42(11):878–880
  22. World Health Organization. Reducing risks, promoting healthy life. World Health Organization, Geneva 2002 http://www.who.int/whr/2002/en/Overview-E.pdfAccessed June 9, 2009
  23. World Health Organization. Obesity: Preventing and Managing the Global Epidemic (Report on a WHO consultation on obesity: June 3-5, 1997; Geneva, Switzerland). WHO/NUT/NCD/98.1, Geneva, 1998 http://www.nutritionsociety.org/documents/20051116reading3Clin.pdfAccessed June 9, 2009
  24. Guidelines Subcommittee. 1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension (Guidelines subcommittee). J Hypertens. 1999;17(2):151–183
  25. Opie LH, Seedat YK. Hypertension in sub-Saharan African populations. Circulation. 2005;112(23):3562–3568
  26. Cooper R, Rotimi C, Ataman S, et al. The prevalence of hypertension in seven populations of West African origin. Am J Public Health. 1997;87(2):160–168
  27. Teo KK, Ounpuu S, Hawken S, et al. Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control study. Lancet. 2006;368(9536):647–658
  28. Jafar TH, Chaturvedi N, Pappas G. Prevalence of overweight and obesity and their association with hypertension and diabetes mellitus in an Indo-Asian population. CMAJ. 2006;175(9):1071–1077
  29. Unwin N, Harland J, White M, et al. Body mass index, waist circumference, waist-hip ratio, and glucose intolerance in Chinese and Europid adults in Newcastle, UK. J Epidemiol Community Health. 1997;51(2):160–166
  30. Razak F, Anand SS, Shannon H, et al. Defining obesity cut points in a multiethnic population. Circulation. 2007;115(16):2111–2118
  31. Alberti KG, Zimmet P, Shaw J IDF Epidemiology Task Force Consensus Group. The metabolic syndrome—a new worldwide definition. Lancet. 2005;366(9491):1059–1062
  32. Esmaillzadeh A, Mirmiran P, Azizi F. Waist-to-hip ratio is a better screening measure for cardiovascular risk factors than other anthropometric indicators in Tehranian adult men. Int J Obes Relat Metab Disord. 2004;28(10):1325–1332
  33. Seedat YK. Hypertension in developing nations in Sub-Saharan Africa. J Hum Hypertens. 2000;14(10-11):739–747
  34. Tiago AD, Samani NJ, Candy GP, et al. Angiotensinogen gene promoter region variant modifies body size-ambulatory blood pressure relations in hypertension. Circulation. 2002;106(12):1483–1487
  35. Touyz RM, Milne FJ, Seftel HC, Reinach SG. Magnesium, calcium, sodium and potassium status in normotensive and hypertensive Johannesburg residents. S Afr Med J. 1987;72(6):377–381
  36. Campese VM, Parise M, Karubian F, Bigazzi R. Abnormal renal hemodynamics in black salt-sensitive patients with hypertension. Hypertension. 1991;18(6):805–812
  37. Barker DJ, Osmond C. Low birth weight and hypertension. BMJ. 1988;297(6641):134–135
  38. Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ. 1989;298(6673):564–567
  39. Moore VM, Cockington RA, Ryan P, Robinson JS. The relationship between birth weight and blood pressure amplifies from childhood to adulthood. J Hypertens. 1999;17(7):883–888
  40. Law CM, Shiell AW, Newsome CA, et al. Fetal, infant, and childhood growth and adult blood pressure: a longitudinal study from birth to 22 years of age. Circulation. 2002;105(9):1088–1092
  41. Law CM, Egger P, Dada O, et al. Body size at birth and blood pressure among children in developing countries. Int J Epidemiol. 2001;30(1):52–57
  42. Levitt NS, Steyn K, De Wet T, et al. An inverse relation between blood pressure and birth weight among 5 year old children from Soweto, South Africa. J Epidemiol Community Health. 1999;53(5):264–268
  43. Brenner BM, Chertow GM. Congenital oligonephropathy: an inborn cause of adult hypertension and progressive renal injury?. Curr Opin Nephrol Hypertens. 1993;2(5):691–695
  44. Barker DJ, Shiell AW, Barker ME, Law CM. Growth in utero and blood pressure levels in the next generation. J Hypertens. 2000;18(7):843–846
  45. Eriksson JG, Forsen TJ, Kajantie E, Osmond C, Barker DJ. Childhood growth and hypertension in later life. Hypertension. 2007;49(6):1415–1421
  46. Hossain MP, Goyder EC, Rigby JE, El Nahas M. CKD and poverty: a growing global challenge. Am J Kidney Dis. 2009;53(1):166–174
  47. Schneider M, Bradshaw D, Steyn K, Norman R, Laubscher R. Poverty and non-communicable diseases in South Africa. Scand J Public Health. 2009;37(2):176–186
  48. Sun Z, Zheng L, Wei Y, et al. The prevalence of prehypertension and hypertension among rural adults in Liaoning Province of China. Clin Cardiol. 2007;30(4):183–187
  49. Jafar TH. Hypertension and kidney disease in Asia. Curr Opin Nephrol Hypertens. 2006;15(3):291–295
  50. Metcalf CA, Hoffman MN, Steyn K, Katzenellenbogen JM, Fourie JM. Design and baseline characteristics of a hypertension intervention program in a South African village. J Hum Hypertens. 1996;10(1):21–26
  51. Murray CJ, Lauer JA, Hutubessy RC, et al. Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and regional analysis on reduction of cardiovascular-disease risk. Lancet. 2003;361(9359):717–725
  52. Murray CJ, Lopez AD. Mortality by cause for eight regions of the world: global burden of disease study. Lancet. 1997;349(9061):1269–1276
  53. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: global burden of disease study. Lancet. 1997;349(9064):1498–1504
  54. Bakris GL, Ritz E. World Kidney Day 2009: Hypertension and kidney disease is a marriage that should be prevented. Am J Kidney Dis. 2009;53(3):373–376
  55. World Health Organization. Stepwise Approach to surveiLLance (STEPS) Program. http://www.who.int/chp/steps/en/Accessed August 21, 2009
  56. Brown IJ, Tzoulaki I, Candeias V, Elliott P. Salt intakes around the world: implications for public health. Int J Epidemiol. 2009;38(3):791–813
  57. Akpolat T, Kadi R, Utaş C. Hypertension, salt, and bread [letter]. Am J Kidney Dis. 2009;53(6):1103
  58. Adrogué HJ, Madias NE. Sodium and potassium in the pathogenesis of hypertension. N Engl J Med. 2007;356(19):1966–1978
  59. INTERSALT. An international study of electrolyte excretion and blood pressure (Results for 24 hour urinary sodium and potassium excretion). INTERSALT Cooperative Research Group BMJ. 1988;297(6644):319–328
  60. Hyman DJ, Pavlik VN. Poor hypertension control: let's stop blaming the patients. Cleve Clin J Med. 2002;69(10):793–799
  61. Hagemeister J, Schneider CA, Barabas S, et al. Hypertension guidelines and their limitations—the impact of physicians' compliance as evaluated by guideline awareness. J Hypertens. 2001;19(11):2079–2086
  62. Jafar TH, Jessani S, Jafary FH, et al. General practitioners' approach to hypertension in urban Pakistan: disturbing trends in practice. Circulation. 2005;111(10):1278–1283
  63. Qureshi NN, Hatcher J, Chaturvedi N, Jafar TH Hypertension Research Group. Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. BMJ. 2007;335(7628):1030–1038
  64. Mani MK. Nephrologists sans frontiers: preventing chronic kidney disease on a shoestring. Kidney Int. 2006;70(5):821–823
  65. Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ. 2003;326(7404):1427
  66. Indian Polycap Study (TIPS)Yusuf S, Pais P, Afzal R, et al. Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet. 2009;373(9672):1341–1351
  67. Johnson AD, Gong Y, Wang D, et al. Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. Clin Pharmacol Ther. 2009;85(1):36–44
  68. Johnson JA, Boerwinkle E, Zineh I, et al. Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study. Am Heart J. 2009;157(3):442–449

 Originally published online as doi:10.1053/j.ajkd.2009.06.044 on December 7, 2009.

PII: S0272-6386(09)01082-8

doi: 10.1053/j.ajkd.2009.06.044

American Journal of Kidney Diseases
Volume 55, Issue 3 , Pages 590-598 , March 2010