American Journal of Kidney Diseases
Volume 55, Issue 1 , Pages 192-197 , January 2010

Crystal-Induced Kidney Disease in 2 Kidney Transplant Recipients

  • Ravi Parasuraman, MD

      Affiliations

    • Division of Nephrology and Transplantation, William Beaumont Hospital, Royal Oak, MI
    • Corresponding Author InformationAddress correspondence to Ravi Parasuraman, MD, Kidney Transplant Outreach Program, Division of Nephrology and Transplantation, William Beaumont Hospital, Royal Oak, MI 48703
    • ,
  • K.K. Venkat, MD

      Affiliations

    • Division of Nephrology and Hypertension, Henry Ford Hospital, Detroit, MI

Received 19 December 2008 ,Accepted 14 August 2009.

  • Image Result

    Kidney allograft biopsy specimen from patient 1. Hematoxylin and eosin stain shows intratubular crystal deposition with multifocal tubular injury and interstitial inflammation.

    Kidney allograft biopsy specimen from patient 1. Hematoxylin and eosin stain shows intratubular crystal deposition with multifocal tubular injury and interstitial inflammation.

  • Image Result

    Characterization of crystals in the kidney allograft biopsy specimen from patient 1. (A) Hematoxylin and eosin stain shows intratubular crystal deposition with tubulitis. (B) Birefringent oxalate crys

    Characterization of crystals in the kidney allograft biopsy specimen from patient 1. (A) Hematoxylin and eosin stain shows intratubular crystal deposition with tubulitis. (B) Birefringent oxalate crystals are visible under polarized light.

  • Image Result
    Kidney allograft biopsy specimen from patient 2. (A) Hematoxylin and eosin stain shows extensive intratubular crystal deposition typical of calcium phosphate. (B) von Kossa stain for phosphates shows

    Kidney allograft biopsy specimen from patient 2. (A) Hematoxylin and eosin stain shows extensive intratubular crystal deposition typical of calcium phosphate. (B) von Kossa stain for phosphates shows the extent of calcium phosphate crystal deposition.

  • Image Result
    Metabolic pathway of vitamin C (ascorbic acid). Source for structures: PubChem (pubchem.ncbi.nlm.nih.gov).

    Metabolic pathway of vitamin C (ascorbic acid). Source for structures: PubChem (pubchem.ncbi.nlm.nih.gov).

 Originally published online as doi:10.1053/j.ajkd.2009.08.012 on November 2, 2009.

PII: S0272-6386(09)01144-5

doi: 10.1053/j.ajkd.2009.08.012

American Journal of Kidney Diseases
Volume 55, Issue 1 , Pages 192-197 , January 2010

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