American Journal of Kidney Diseases
Volume 56, Issue 1 , Pages 175-180 , July 2010

Incidental Discovery of a Renal Cell Carcinoma on Native Kidney Biopsy

  • C. John Sperati, MD, MHS

      Affiliations

    • Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD
    • Corresponding Author InformationAddress correspondence to C. John Sperati, MD, MHS, The Johns Hopkins University School of Medicine, 1830 E Monument St, Rm 416, Baltimore, MD 21205
    • ,
  • Nada Alachkar, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD
    • ,
  • Ronald Rodriguez, MD, PhD

      Affiliations

    • Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD
    • ,
  • Mark Haas, MD, PhD

      Affiliations

    • Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA
    • ,
  • Michael J. Choi, MD

      Affiliations

    • Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD

Received 23 March 2009 ,Accepted 25 August 2009.

References 

  1. Levey AS, Greene T, Kusek JW, Beck GJ. A simplified equation to predict GFR from S-creatinine [abstract]. J Am Soc Nephrol. 2000;11:155A
  2. Pankhurst T, Howie AJ, Adu D, Wallace DM, Lipkin GW. Incidental neoplasms in renal biopsies. Nephrol Dial Transplant. 2006;21:64–69
  3. Ravine D, Gibson RN, Donlan J, Sheffield LJ. An ultrasound renal cyst prevalence survey: specificity data for inherited renal cystic diseases. Am J Kidney Dis. 1993;22:803–807
  4. Terada N, Ichioka K, Matsuta Y, Okubo K, Yoshimura K, Arai Y. The natural history of simple renal cysts. J Urol. 2002;167:21–23
  5. Tickoo SK, dePeralta-Venturina MN, Harik LR, et al. Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol. 2006;30:141–153
  6. Cossu-Rocca P, Eble JN, Zhang S, Martignoni G, Brunelli M, Cheng L. Acquired cystic disease-associated renal tumors: an immunohistochemical and fluorescence in situ hybridization study. Mod Pathol. 2006;19:780–787
  7. Emmett JL, Levine SR, Woolner LB. Co-existence of renal cyst and tumour: incidence in 1,007 cases. Br J Urol. 1963;35:403–410
  8. Weitzner S. Clear cell carcinoma of the free wall of a simple renal cyst. J Urol. 1971;106:515–517
  9. Sufrin G, Etra W, Gaeta J, Merrin CE. Hypernephroma arising in wall of simple renal cyst. Urology. 1975;6:507–510
  10. Lin CJ, Chen YC, Chen HH, Wu CJ, Hsu JM. Renal cell carcinoma presenting as a huge simple renal cyst. Med Oncol. 2008;25:104–106
  11. Marumo K, Horiguchi Y, Nakagawa K, et al. Incidence and growth pattern of simple cysts of the kidney in patients with asymptomatic microscopic hematuria. Int J Urol. 2003;10:63–67
  12. Israel GM, Bosniak MA. An update of the Bosniak renal cyst classification system. Urology. 2005;66:484–488
  13. Israel GM, Bosniak MA. Follow-up CT of moderately complex cystic lesions of the kidney (Bosniak category IIF). AJR Am J Roentgenol. 2003;181:627–633
  14. In:  Eble JN,  Sauter G,  Epstein JI editor. World Health Organization Classification of Tumours (Pathology and Genetics of Tumours of the Urinary System and Male Genital Organ). Lyon, France: IARC Press; 2004;
  15. Ruppert-Kohlmayr AJ, Uggowitzer M, Meissnitzer T, Ruppert G. Differentiation of renal clear cell carcinoma and renal papillary carcinoma using quantitative CT enhancement parameters. AJR Am J Roentgenol. 2004;183:1387–1391
  16. Crispen PL, Uzzo RG. The natural history of untreated renal masses. BJU Int. 2007;99:1203–1207
  17. Crispen PL, Wong YN, Greenberg RE, Chen DY, Uzzo RG. Predicting growth of solid renal masses under active surveillance. Urol Oncol. 2008;26:555–559
  18. Bensalah K, Pantuck AJ, Crepel M, et al. Prognostic variables to predict cancer-related death in incidental renal tumours. BJU Int. 2008;102:1376–1380
  19. Collins S, McKiernan J, Landman J. Update on the epidemiology and biology of renal cortical neoplasms. J Endourol. 2006;20:975–985
  20. Kunkle DA, Crispen PL, Li T, Uzzo RG. Tumor size predicts synchronous metastatic renal cell carcinoma: implications for surveillance of small renal masses. J Urol. 2007;177:1692–1696discussion, 1697
  21. Chawla SN, Crispen PL, Hanlon AL, Greenberg RE, Chen DY, Uzzo RG. The natural history of observed enhancing renal masses: meta-analysis and review of the world literature. J Urol. 2006;175:425–431
  22. Kunkle DA, Crispen PL, Chen DY, Greenberg RE, Uzzo RG. Enhancing renal masses with zero net growth during active surveillance. J Urol. 2007;177:849–853discussion, 853-854
  23. Silverman SG, Gan YU, Mortele KJ, Tuncali K, Cibas ES. Renal masses in the adult patient: the role of percutaneous biopsy. Radiology. 2006;240:6–22
  24. Hui GC, Tuncali K, Tatli S, Morrison PR, Silverman SG. Comparison of percutaneous and surgical approaches to renal tumor ablation: metaanalysis of effectiveness and complication rates. J Vasc Interv Radiol. 2008;19:1311–1320
  25. Boss A, Clasen S, Kuczyk M, Schick F, Pereira PL. Image-guided radiofrequency ablation of renal cell carcinoma. Eur Radiol. 2007;17:725–733
  26. Georgiades CS, Hong K, Bizzell C, Geschwind JF, Rodriguez R. Safety and efficacy of CT-guided percutaneous cryoablation for renal cell carcinoma. J Vasc Interv Radiol. 2008;19:1302–1310
  27. Kunkle DA, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer. 2008;113:2671–2680
  28. Weight CJ, Kaouk JH, Hegarty NJ, et al. Correlation of radiographic imaging and histopathology following cryoablation and radio frequency ablation for renal tumors. J Urol. 2008;179:1277–1281discussion, 1281-1283

 Originally published online as doi:10.1053/j.ajkd.2009.08.018 on November 2, 2009.

PII: S0272-6386(09)01186-X

doi: 10.1053/j.ajkd.2009.08.018

American Journal of Kidney Diseases
Volume 56, Issue 1 , Pages 175-180 , July 2010

Article Tools

* Image Usage & Resolution