American Journal of Kidney Diseases
Volume 56, Issue 2 , Pages 394-398 , August 2010

Recurrence of Amyloidosis in a Kidney Transplant

  • Sanjeev Sethi, MD, PhD

      Affiliations

    • Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
    • Corresponding Author InformationAddress correspondence to Sanjeev Sethi, MD, PhD, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905
    • ,
  • Fernando C. Fervenza, MD

      Affiliations

    • Department of Internal Medicine, Division of Hypertension and Nephrology, Mayo Clinic, Rochester, MN
    • ,
  • Dylan Miller, MD

      Affiliations

    • Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
    • ,
  • Suzanne Norby, MD

      Affiliations

    • Department of Internal Medicine, Division of Hypertension and Nephrology, Mayo Clinic, Rochester, MN
    • ,
  • Nelson Leung, MD

      Affiliations

    • Department of Internal Medicine, Division of Hypertension and Nephrology, Mayo Clinic, Rochester, MN

Received 13 May 2009 ,Accepted 30 October 2009.

References 

  1. Rodriguez FJ, Gamez JD, Vrana JA, et al. Immunoglobulin derived depositions in the nervous system: novel mass spectrometry application for protein characterization in formalin-fixed tissues. Lab Invest J Tech Methods Pathol. 2008;88:1024–1037
  2. Sethi S, Gamez JD, Vrana JA, et al. Glomeruli of dense deposit disease contain components of the alternative and terminal complement pathway. Kidney Int. 2009;75(9):952–960
  3. El-Zoghby Z, Lager D, Gregoire J, et al. Intra-tubular amyloidosis. Kidney Int. 2007;72:1282–1288
  4. Dember LM. Amyloidosis-associated kidney disease. J Am Soc Nephrol. 2006;17:3458–3471
  5. Gillmore JD, Lachmann HJ, Rowczenio D, et al. Diagnosis, pathogenesis, treatment, and prognosis of hereditary fibrinogen A alpha-chain amyloidosis. J Am Soc Nephrol. 2009;20:444–451
  6. Lane SW, Goodman HJ, Francis L, et al. Hereditary fibrinogen A alpha-chain amyloidosis. Pathology. 2006;38:380–382
  7. Hamidi Asl L, Liepnieks JJ, Uemichi T, et al. Renal amyloidosis with a frame shift mutation in fibrinogen Aalpha-chain gene producing a novel amyloid protein. Blood. 1997;90:4799–4805
  8. Uemichi T, Liepnieks JJ, Benson MD. Hereditary renal amyloidosis with a novel variant fibrinogen. J Clin Invest. 1994;93:731–736
  9. Benson MD, Liepnieks J, Uemichi T, et al. Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain. Nat Genet. 1993;3:252–255
  10. Miller DV, Dogan A, Sethi S. New-onset proteinuria with massive amorphous glomerular deposits. Am J Kidney Dis. doi: 10.1053/j.ajkd.2009.05.015.
  11. Mousson C, Heyd B, Justrabo E, et al. Successful hepatorenal transplantation in hereditary amyloidosis caused by a frame-shift mutation in fibrinogen Aalpha-chain gene. Am J Transplant. 2006;6:632–635
  12. Gillmore JD, Booth DR, Rela M, et al. Curative hepatorenal transplantation in systemic amyloidosis caused by the Glu526Val fibrinogen alpha-chain variant in an English family. QJM. 2000;93:269–275

 Originally published online as doi:10.1053/j.ajkd.2009.10.061 on February 22, 2010.

PII: S0272-6386(09)01594-7

doi: 10.1053/j.ajkd.2009.10.061

American Journal of Kidney Diseases
Volume 56, Issue 2 , Pages 394-398 , August 2010

Article Tools

* Image Usage & Resolution