American Journal of Kidney Diseases
Volume 59, Issue 2 , Pages 186-195 , February 2012

Effect of Vitamin K2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial

  • Ralf Westenfeld, MD

      Affiliations

    • Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Düsseldorf, Düsseldorf, Germany
    • R.W. and T.K. contributed equally to this work.
    • ,
  • Thilo Krueger, MD

      Affiliations

    • Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany
    • R.W. and T.K. contributed equally to this work.
    • Corresponding Author InformationAddress correspondence to Thilo Krueger, MD, Department of Nephrology and Clinical Immunology, University Clinic of the RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    • ,
  • Georg Schlieper, MD

      Affiliations

    • Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany
    • ,
  • Ellen C.M. Cranenburg, MD, PhD

      Affiliations

    • VitaK, Maastricht University, Maastricht, the Netherlands
    • ,
  • Elke J. Magdeleyns, BSc

      Affiliations

    • VitaK, Maastricht University, Maastricht, the Netherlands
    • ,
  • Stephan Heidenreich, MD

      Affiliations

    • KfH Dialysis Unit Aachen, Aachen, Germany
    • ,
  • Stefan Holzmann, MD

      Affiliations

    • Dialysis Unit Erkelenz, Erkelenz, Germany
    • ,
  • Cees Vermeer, PhD

      Affiliations

    • VitaK, Maastricht University, Maastricht, the Netherlands
    • ,
  • Willi Jahnen-Dechent, PhD

      Affiliations

    • Helmholtz-Institute, RWTH Aachen, Aachen, Germany
    • ,
  • Markus Ketteler, MD

      Affiliations

    • Division of Nephrology, Hospital Coburg, Coburg, Germany
    • ,
  • Jürgen Floege, MD

      Affiliations

    • Division of Nephrology and Clinical Immunology, RWTH Aachen University, Aachen, Germany
    • J.F. and L.J.S. contributed equally to this work.
    • ,
  • Leon J. Schurgers, PhD

      Affiliations

    • Department of Biochemistry, Maastricht University, Maastricht, the Netherlands
    • J.F. and L.J.S. contributed equally to this work.
    • Corresponding Author InformationLeon J. Schurgers, PhD, Department of Biochemistry, CARIM, Maastricht University, Universiteitssingel 50, 6200 MD Maastricht, the Netherlands

Received 29 April 2011 ,Accepted 6 October 2011.

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 Originally published online December 12, 2011.

 Trial registration: ClinicalTrials.gov; study number: NCT01407601

PII: S0272-6386(11)01570-8

doi: 10.1053/j.ajkd.2011.10.041

American Journal of Kidney Diseases
Volume 59, Issue 2 , Pages 186-195 , February 2012

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