Core Curriculum in Nephrology
Installments of the Core Curriculum in Nephrology provide trainees in nephrology with a strong knowledge base in core topics in the specialty by providing an overview of the topic and citing key references, including the foundational literature that led to current clinical approaches.
- Chronic kidney disease (CKD)–mineral and bone disorder (CKD-MBD) is a term that encompasses a constellation of abnormalities seen in progressive kidney disease that include altered levels of calcium, phosphorus, parathyroid hormone (PTH), and vitamin D; disturbances in bone modeling and remodeling, with the associated development of fractures or impaired linear bone growth (in children); and extraskeletal calcification in soft tissues and arteries. The kidney is responsible for maintenance of serum calcium and phosphorus levels within the normal range in people without kidney disease.
- Calcium (Ca), phosphorus (P), and magnesium (Mg) homeostasis is controlled by serum concentrations of the ion and regulating hormones that act on 3 target organs: bone, intestine, and kidney.